نتایج جستجو برای: nph insulin

تعداد نتایج: 183665  

2015
Geremia B. Bolli Paola Lucidi Francesca Porcellati Anna Marinelli Andreoli Ilaria Carriero Paola Candeloro Patrizia Cioli Carmine G. Fanelli

PK and PDwere assessed after subcutaneous injection of NPH insulin 0.35 units/kg at steady-state by pen either resuspended (R+, tipping of insulin pen 20 times) or nonresuspended (penmaintained in fixed position either horizontally [Rhorizontal] or vertically with tip up [Rup] or tip down [Rdown]). Eleven subjectswith type 1 diabetes (age 31.56 12 years, diabetes duration 17.56 7.7 years, BMI 2...

Journal: :Diabetes care 2007
Klas Ekström Jenny Salemyr Ingmar Zachrisson Christine Carlsson-Skwirut Eva Ortqvist Peter Bang

OBJECTIVE We sought to test the hypothesis that start of insulin glargine with sustained nightly insulin action results in changes in circulating concentrations of IGF-I and IGF binding proteins (IGFBPs) in adolescents with type 1 diabetes-changes that may support improvement of A1C. RESEARCH DESIGN AND METHODS Twelve pubertal adolescents with type 1 diabetes and initially on NPH insulin were...

2012
Thomas Donner Miguel Muñoz

Type 2 diabetes is characterized by insulin resistance and impaired insulin secretion at diagnosis and by progressive β-cell dysfunction over time. Insulin therapy is thus frequently required during the course of the disease to maintain glycemic control and prevent diabetes complications. Insulin should be initiated when alternative antihyperglycemic agents have failed or when symptomatic or ma...

Journal: :Primary care diabetes 2010
Luigi Meneghini Andreas Liebl Martin J Abrahamson

Insulin detemir provides prolonged, reproducible blood glucose reduction through a mechanism unique among basal insulins. It was originally studied clinically in predominantly basal + bolus regimens and found to be associated with a low risk of hypoglycaemia compared to insulin NPH, and reduced weight gain compared to other basal insulins. Insulin detemir has been increasingly studied in basal-...

Journal: :veterinary research forum 2012
somaye javidanpour seyed reza fatemi tabtabaei amir siahpoosh hasan morovati ali shahriari

there is some report about the hypoglycemic effect of juglans rejia l. leaf in alloxan induced diabetic rats and hypoglycemic effect of its fruit peel administered intra peritoneally. thirty male wistar rats divided into five groups, to evaluate the hypoglycemic and pancreas β-cells regenerative effects of oral methanolic extracts of leaf and fruit peel of walnut. rats were made diabetic by int...

Journal: :American family physician 2004
Jennifer A Mayfield Russell D White

Type 2 diabetes is characterized by progressive beta-cell failure. Indications for exogenous insulin therapy in patients with this condition include acute illness or surgery, pregnancy, glucose toxicity, contraindications to or failure to achieve goals with oral antidiabetic medications, and a need for flexible therapy. Augmentation therapy with basal insulin is useful if some beta-cell functio...

Journal: :Expert opinion on pharmacotherapy 2010
Michael Gejl Jensen Mikkel Hansen Birgitte Brock Jørgen Rungby

IMPORTANCE OF THE FIELD Most guidelines suggest that failure of oral antidiabetic drugs should be followed by the addition of a basal insulin with aggressive titration of the dose. In most countries, neutral protamine Hagedorn (NPH)-insulin, glargine and detemir are the only choices. Clinical trials show that the metabolism and metabolic outcomes after treatment with intermediate- or long-actin...

2016
João Leopoldo Oliveira Araujo Mariana Donato Pereira Cristiane de Cássia Bergamaschi Fernando de Sá Del Fiol Luciane Cruz Lopes Maria Inês de Toledo Silvio Barberato-Filho

BACKGROUND In 2011, private pharmacies associated to the Brazilian Ministry of Health provided patients with two types of insulin (regular human insulin and isophane insulin or NPH) and three oral antidiabetic medications (5 mg glibenclamide and 500 and 850 mg metformin) free of charge. The aim was to evaluate the impact of the "Health Has No Price" Program [Saúde Não Tem Preço (SNTP)] for acce...

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