We report the case of a Moroccan boy with mental retardation, hyperactivity, epilepsy, developmental problems and behavioural disorders. Cytogenetic analysis showed the presence of a supernumerary marker chromosome. Molecular cytogenetics allowed us to determine the marker as an inverted duplication of chromosome 15. It is the first case of a Moroccan patient with tetrasomy 15q in which fluores...

The aim of this study is to show the importance and significance of goat milk . Goat is known as poor man’s cow .It play a vital role in the socio-economic structure of rural poor. Goat milk contains higher amount of Ca, Mg and P than cow and human milk but vitamin D, vitamin B12 and folate contents are less. Although fat and protein is somewhat low in goat milk than cow milk, but there is a no...

The peptide hormone ghrelin is the only known protein modified with an O-linked octanoyl side group, which occurs on its third serine residue. This modification is crucial for ghrelin's physiological effects including regulation of feeding, adiposity, and insulin secretion. Despite the crucial role for octanoylation in the physiology of ghrelin, the lipid transferase that mediates this novel mo...

Ghrelin is the only known hormone posttranslationally modified with an acylation. This modification is crucial for most of ghrelin's physiological effects and is catalyzed by the polytopic enzyme ghrelin O-acyltransferase (GOAT). The aim of this study was to characterize GOAT in a teleost model, goldfish (Carassius auratus). First, the full-length cDNA sequence was obtained by RT-PCR and rapid ...

The status, economics and prospects of commercialization of goat production in the country have been analyzed using primary data from 18 commercial goat farms in different states. It has been revealed that several large and progressive farmers, businessman and industrialists have adopted commercial goat farming. The entry of large farmers, who have better access to technical knowledge, resource...

Ghrelin is a 28 amino acid, appetite-stimulating peptide hormone secreted by the food-deprived stomach. Serine-3 of ghrelin is acylated with an eight-carbon fatty acid, octanoate, which is required for its endocrine actions. Here, we identify GOAT (Ghrelin O-Acyltransferase), a polytopic membrane-bound enzyme that attaches octanoate to serine-3 of ghrelin. Analysis of the mouse genome revealed ...

BACKGROUND Traditional approaches for generating goat pluripotent stem cells (iPSCs) suffer from complexity and low preparation efficiency. Therefore, we tried to derive goat iPSCs with a new method by transfecting exogenous Oct4, Sox2, Klf4 and c-Myc mRNAs into goat embryonic fibroblasts (GEFs), and explore the mechanisms regarding the transcription regulation of the reprogramming factors in g...

This paper examines the role of cattle in Roman economy acrossthe region river Rhine (the Netherlands, western and south-western Germany, eastern France, northern Switzerland). large marked frontier Empire. Taxonomic data (over 606,000 animal remains – cattle, sheep/goat pig) are considered, biometrical (nearly 15,000 bone measurements) analysed through log-ratio or LSI-technique, order to look...