Introduction: The purpose of this work was to study the ability of MRI normoxic polymer gel dosimetry for evaluating the dose distribution in HDR brachytherapy of esophagial cancer at Imam Reza brachytherapy center (Mashhad, Iran). Materials and Methods: Initially, 2liters of normoxic gel (MAGIC) was fabricated and then poured into 12 calibration test tubes and placed in a perspex walled phanto...

Background: Radiation-sensitive polymer gels are among the most promising three-dimensional dose verification tools and tissue-like developed to date. Among the special features of this type of dosimeters, is be doped with other elements or chemicals which made them appropriate for investigating of dose enhancement with contrast agents, by high atomic number. Material and Methods: In this study...

Abstract Reactive oxygen species (ROS) are not only toxic agents but also potent signaling molecules. NADPH oxidases the sole enzymes to generate ROS playing an important role in redox signaling. They closely interact several ways with hypoxia-inducible transcription factors of HIF family. This network is active under normoxic and hypoxic conditions as regulator homeostasis. Members oxidases-HI...