OBJECTIVE To evaluate the role of self-efficacy, anticipated negative consequences, and relationship quality in patient-initiated sex partner notification following treatment for sexually transmitted infections. SUBJECTS Two hundred forty-one 13- to 20-year-old subjects (83% women; 83% African American) diagnosed with gonorrhea, chlamydia, trichomonas, or nongonococcal urethritis. Subjects we...

In the United States, Chlamydia trachomatis is the most common sexually transmitted bacterial pathogen. There are estimated to be 3 million new infections each year. Chlamydial genital tract infections are a major cause of urethritis, cervicitis, and pelvic inflammatory disease (PID) in women and are an important cause of ectopic pregnancy, infertility, and chronic pelvic pain. Chlamydial infec...

To clarify the clinical efficacy of a single oral 2 g dose of azithromycin extended-release for heterosexual male patients with urethritis, and the current antimicrobial sensitivity of Neisseria gonorrhoeae to azithromycin, a prospective clinical trial was conducted from 2011-2013. In patients with gonococcal urethritis, the eradication rate was 90.9% (30 of 33). The susceptibility rates of iso...

In a double-blind comparison of two regimens of triple tetracycline (Deteclo, Lederle) in the treatment of nongonococcal urethritis, 68 (88.6%) of 70 patients treated with one tablet twice for 21 days and seen four weeks after starting therapy had satisfactory results. This was significantly better than the findings among the 73 patients treated with one tablet twice daily for seven days and fo...

The older terminology of ‘venereal diseases’ (VDs) largely has been superseded in the past 50 years by ‘sexually transmitted diseases’ (STDs) and more recently by ‘sexually transmitted infections’ (STIs). To some, venereal diseases came to be viewed as a narrow and pejorative term limited to gonorrhea, syphilis, chancroid, lymphogranuloma venereum and granuloma inguinale and related VD control ...

Since the wide-range orally administered antibiotics, aureomycin (Finland and others, 1948) and terramycin (Willcox, 1951; Willcox and Findlay, 1952), were first reported as effective in nongonococcal urethritis the question has arisen of their relative efficacy. In a previous paper a comparison was made of the relative efficacy of terramycin, aureomycin, chloramphenicol, sulphonamides, strepto...

The place of oral oxytetracycline hydrochloride (Terramycin) therapy in the treatment of nongonococcal urethritis (N.G.U.) is well established (Harkness, 1953; Willcox, 1957; Morton and Read, 1957). Success rates of about 85 per cent. are above those obtained by other antibiotics, sulphomanides, or a combination of these. The trial reported below was undertaken at a time when a degree of penici...

Genital mycoplasmas are implicated in pelvic inflammatory diseases, puerperal infection, septic abortions, low birth weight, nongonococcal urethritis and prostatitis as well as spontaneous abortion and infertility in women. There is paucity of data on colonisation of genital mycoplasma in women and their drug sensitivity patterns. The aim of our study was to determine the prevalence of genital ...

There is at present little agreement about the significance of the "T" strain mycoplasma in genito-urinary infections. Workers who have studied the problem have expressed opinions which vary from its confident indictment as a cause of "nonspecific urethritis" to its dismissal as simple evidence of promiscuity or as completely irrelevant. Shepard (1956) and Shepard, Lunceford, and Campbell (1964...

Adhesins and adhesin-related accessory proteins of pathogenic mycoplasmas are required for cytadherence and the subsequent development of disease pathology. The classic example has been Mycoplasma pneumoniae, which causes primary atypical pneumonia in humans. Mutants of M. pneumoniae defective in adhesins (P1 and P30) or in adherence-accessory proteins (HMW1 through HMW4) are unable to colonize...