Psychogenic nonepileptic seizures (PNES) are events commonly encountered by primary care physicians, neurologists, pediatricians, and emergency medicine physicians in their practices, yet there continues to be significant variability in the way they are evaluated, diagnosed, and treated. Lack of understanding this condition and limited data on long-term outcome from current treatment paradigms ...

Perampanel (PER) is the first-in-class selective, noncompetitive α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor antagonist that has been licensed and marketed as antiepileptic drug (AED) indicated for patients with partial-onset and primary generalized tonic-clonic seizures. A positive effect was reported in some patients with epileptic myoclonic jerks in idiopathic genera...

Electroencephalogram (EEG) recording is essential in the evaluation of complex movement and behaviors during sleep, but particular for differentiating epileptic versus nonepileptic events. In general, epileptiform discharges occur with greater density first few nonerapid eye cycles, approximately 12% to 20% seizures exclusively at night. This review examines epilepsy types syndromes whose prese...