Non-immune hemolytic anemia (NIHA) is characterized by positive routine hemolytic tests but negative anti-human immunoglobulin (Coombs) test. Hereditary non-immune hemolysis includes disorders of erythrocytic enzymes, membrane, hemoglobin (qualitative and quantitative disorders), as well as the rare hereditary forms of thrombotic microangiopathies. Acquired NIHA includes paroxysmal nocturnal he...

Avian, murine, feline, and human retroviruses frequently cause immunosuppression in their respective hosts (1, 2). The mechanisms by which immune reactivity is impaired remain speculative. Virus infection often results in immune hyporeactivity, but in some instances inactivated virus causes suppression independently of cellular infection (3, 4). Thus, it appears likely that some viral proteins ...

The innate immune system is the first line of defense in response to nonself and danger signals from microbial invasion or tissue injury. It is increasingly recognized that each organ uses unique sets of cells and molecules that orchestrate regional innate immunity. The cells that execute the task of innate immunity are many and consist of not only "professional" immune cells but also nonimmune...

New-onset psychosis in children represents a complex presenting symptom. Psychosis can be attributable to a combination of factors and etiologies, and all possible causes must be systematically examined. There is growing evidence that a proportion of psychosis/ psychiatric manifestations in children may be immunemediated, and physicians should consider this etiology in each presentation of firs...

Avian, murine, feline, and human retroviruses frequently cause immunosuppression in their respective hosts (1, 2). The mechanisms by which immune reactivity is impaired remain speculative. Virus infection often results in immune hyporeactivity, but in some instances inactivated virus causes suppression independently of cellular infection (3, 4). Thus, it appears likely that some viral proteins ...

The 600-fold increase in the incidence of stroke with advancing age, from 10 per 100,000 below 35 years of age to 6,000 per 100,000 over 75 years (Kurtzke, 1976), is related in the main to the creeping peril of atherosclerosis. However, only a minority of strokes before middle-age can be ascribed to atheroma and in every age-group non-atheromatous causes of cerebral infarction account for a sma...

Abdominal pain constitutes 5% of the causes of emergency admissions and is an important part in the practice of emergency services in all centers. Patients may suffer from acute surgical abdomen, acute abdomen with nonsurgical diseases or acute problems of chronic diseases. Abdominal pain is sometimes associated with acute trauma. Clinical assessment is a process where diagnosis and treatment m...

Non-infectious uveitis is one of the main and insufficiently studied causes disability blindness in patients with immuno-inflammatory diseases. Uveitis associated spondyloarthritis, Behcet’s disease, juvenile idiopathic arthritis, systemic sarcoidosis Vogt-Koyanagi-Harada syndrome are described more often better than others, but pathogenesis different variants their course not well understood. ...

Abdominal pain constitutes 5% of the causes of emergency admissions and is an important part in the practice of emergency services in all centers. Patients may suffer from acute surgical abdomen, acute abdomen with nonsurgical diseases or acute problems of chronic diseases. Abdominal pain is sometimes associated with acute trauma. Clinical assessment is a process where diagnosis and treatment m...