The effect of fiber loss, amplification, and sliding-frequency filters on the evolution of optical pulses in nonlinear optical fibers is considered, this evolution being governed by a perturbed nonlinear Schrödinger (NLS) equation. Approximate ordinary differential equations (ODE's) governing the pulse evolution are obtained using conservation and moment equations for the perturbed NLS equation...

Nuclear import usually relies on the presence of nuclear localization sequences (NLSs). NLSs are recognized by NLS receptors (importins), which target their substrates to the nuclear pore. We identified the NLSs of the yeast ribosomal proteins S22 and S25 and studied the former by mutational analysis. Furthermore, in S25 the nucleolar targeting information was found to overlap with its NLS. Com...

This paper presents a reduced complexity frequency offset estimation method as a modification to the nonlinear least square (NLS) method from [3]. The complexity reduction is achieved by utilizing the Chirp-Z transform. At the same estimation performance, the complexity gain, defined as the complexity ratio between the NLS method and the proposed method, can be approximately from 2 to 9 dependi...

Physiological cell conditions of solid tumors, such as glucose starvation and hypoxia,induce cellular resistance to topoisomerase II-directed drugs. Here, we show that the induction of drug resistance is mediated by nuclear accumulation of proteasomes, large multicatalytic protease complexes. We found that the nuclear proteasome accumulation during glucose starvation was attenuated by stable ex...

— We study the cubic non linear Schrödinger equation (NLS) on compact surfaces. On the sphere S 2 and more generally on Zoll surfaces, we prove that, for s > 1/4, NLS is uniformly well-posed in H s , which is sharp on the sphere. The main ingredient in our proof is a sharp bilinear estimate for Laplace spectral projectors on compact surfaces. Résumé. — Onétudie l'´ equation de Schrödinger non l...

The formation of extreme localizations in nonlinear dispersive media can be explained and described within the framework of nonlinear evolution equations, such as the nonlinear Schrödinger equation (NLS). Within the class of exact NLS breather solutions on a finite background, which describe the modulational instability of monochromatic wave trains, the hierarchy of rational solutions localized...

Arterial smooth muscle cells synthesize matrix macromolecules in response to mechanical stimulation. Exposure to serum lipids also stimulates connective tissue fiber accumulation. To assess the effect of serum lipids on the biosynthetic response to tensile stress, we subjected rabbit aortic smooth muscle cells that were cultured on purified elastin membranes to cyclic stretching and relaxation ...

The plant-infecting geminiviruses deliver their genome and viral proteins into the host cell nucleus. Members of the family Geminiviridae possess either a bipartite genome composed of two approximately 2.6 kb DNAs or a monopartite genome of approximately 3.0 kb DNA. The bipartite genome of Bean dwarf mosaic virus (BDMV) encodes several karyophilic proteins, among them the capsid protein (CP) an...

BACKGROUND We have investigated the possibility and feasibility of producing the HPV-11 L1 major capsid protein in transgenic Arabidopsis thaliana ecotype Columbia and Nicotiana tabacum cv. Xanthi as potential sources for an inexpensive subunit vaccine. RESULTS Transformation of plants was only achieved with the HPV-11 L1 gene with the C-terminal nuclear localization signal (NLS-) encoding re...

We have identified a basic sequence in the N-terminal region of the 67-kDa serum response factor (p67SRF or SRF) responsible for its nuclear localization. A peptide containing this nuclear localization signal (NLS) translocates rabbit immunoglobulin G (IgG) into the nucleus as efficiently as a peptide encoding the simian virus 40 NLS. This effect is abolished by substituting any two of the four...