Background: Diarrhoea is becoming one of the most prominent and troublesome manifestations in COVID-19 infection but no definitive treatment available. So Nitazoxanide was used to see whether it can shorten duration sufferings form related diarrhoea.
 Objective: To efficacy decreasing frequency improving consistency stool Methods: This randomized comparative study done private chambers med...

In view of the serious health problems concerning infectious diseases in heavily populated areas, we followed the strategy of lead compound diversification to evaluate the near-by chemical space for new organic compounds. To this end, twenty derivatives of nitazoxanide (NTZ) were synthesized and tested for activity against Entamoeba histolytica parasites. To ensure drug-likeliness and activity ...

Chronic infection with norovirus is emerging as a significant risk for patients with immunodeficiency - either primary or secondary to therapeutic immunosuppression. Patients with primary immunodeficiency present a range of pathological responses to norovirus infection. Asymptomatic infections occur and differentiating viral carriage or prolonged viral shedding after self-limiting infection fro...