نتایج جستجو برای: niosomal
تعداد نتایج: 214 فیلتر نتایج به سال:
Loratadine is an efficacious, non-drowsy antihistaminic molecule prescribed for allergic skin. The conventional oral dosage form associated with various side effects, limited and variable absorption. present study attempts to improve the effectiveness of drug by formulating a niosome loaded hydrogel loratadine treating Ether injection method was used prepare niosomes using Box Behnken design. P...
Abstract This study aimed to prepare a niosomal gel of green tea ( Camellia sinensis ) extract containing catechins, mostly epigallocatechin-3-gallate (ECGC), as potent antioxidant. Niosomes can increase EGCG's stability and penetration into the skin for better therapeutic effect. were prepared by thin-layer hydration method, evaluated their vesicle shape, particle size, polydispersity index, z...
Clotrimazole, an imidazole derivative antifungal agent is widely used for the treatment of mycotic infections of the genitourinary tract. In order to develop alternative formulation for the vaginal administration of clotrimazole to provide sustained and controlled release of appropriate drug for local vaginal therapy, liposomes/niosomes were evaluated as delivery vehicles. To optimize the prepa...
Breast cancer is the fifth most common cause of death among women worldwide. Resistance to cisplatin is a main challenge in its treatment. Our present aim was to prepare nanoniosomated cisplatin and examine its efficacy in vitro using the BT-20 cell line. Niosome nanoparticles containing cisplatin were prepared by reverse-phase evaporation and characterized by dynamic light scattering (DLS), sc...
Introdution: Doxorubicin is one of the most commonly used drugs in chemotherapy with many side effects; this fact has limited its use. In the present study, based on the knowledge of pharmaceutical nanocarriers, various formulations of the niosomal form of this drug were synthesized and surface optimizations were applied to the final selected formulation. Methods: The present study was an expe...
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