Noise-induced hearing loss (NIHL) is irreversible damage to the ear caused by traumatic noise exposure. This is mainly due to mechanical damage to outer hair cells (OHCs), a type of sensory cell in the inner ear. Recently, prior conditioning with sublethal stressors has been reported to protect the inner ear from acoustic injury, realizing less hearing loss. To explore the stress-actuated prote...

BACKGROUND Noise-induced cochlear epithelium damage can cause hearing loss in industrial workers. In experimental systems, noise induces the release of free radicals and may damage the cochlear sensorial epithelium. Therefore, genes involved in regulating the reactive oxygen species manganese-superoxide dismutase (SOD2) and the antioxidant paraoxonase (PON) could influence cochlea vulnerability...

Exposure to acrylonitrile, a high-production industrial chemical, can promote noise-induced hearing loss (NIHL) in the rat even though this agent does not itself produce permanent hearing loss. The mechanism by which acrylonitrile promotes NIHL includes oxidative stress as antioxidant drugs can partially protect the cochlea from acrylonitrile + noise. Acrylonitrile depletes glutathione levels w...

the aim of the present study was to examine the rate of noise induced hearing loss in a group of punching and cutting section and other occupational groups workers and its relation with sound pressure levels, age and work history. this descriptive, cross-sectional study included 245 workers of the punching and cutting section and other occupational groups of an iranian axial parts factory in 20...