UNLABELLED PREMISE OF THE STUDY Novel markers were developed for pea (Pisum sativum) from pea expressed sequence tags (ESTs) having significant homology to Medicago truncatula gene sequences to investigate genetic diversity, linkage mapping, and cross-species transferability. • METHODS AND RESULTS Seventy-seven EST-derived genic markers were developed through comparative mapping between M....

The loss of the ability for learning and memory is a prominent feature of dementia, which affects millions of individuals all over the world, due to either neurodegenerative diseases or brain injury. Although a lot of information is known about the pathology involved, treatment remains elusive at best. The Black Seed of Nigella sativa has been historically and religiously used for thousands of ...

Metronidazole (MTZ) was the most widely accepted treatment for Blastocystis hominis (B. hominis) with high treatment failure rate, resistance and potential mutagenic and carcinogenic effects so there is urgent need to find out new, effective and safe treatment against B. hominis. The present research aimed to evaluate the therapeutic effect of the aqueous extract of Nigella sativa (NS) at diffe...

The present study was conducted to find out the antibacterial activity of aqueous and organic extracts of Nigella sativa (L.) seeds against various bacterial pathogens, namely; S. aureus, P. aeruginosa and E. coli. Plant extract along with different elicitors such as metal ions and commercial drugs was also screened to see the change in efficacy and potency of the compounds. Among different ext...

We tested a mixture of Tridax procumbens, known for its direct action against Leishmania mexicana, and Allium sativum, known for its immunomodulatory effect, as an alternative to treat cutaneous leishmaniasis. Acute oral toxicity was tested with the Up-and-Down Procedure (UDP) using a group of healthy mice administered with either T. procumbens or A. sativum extracts and compared with a control...

Our previous studies have demonstrated the relaxant, anticholinergic (functional antagonism), antihistaminic, and inhibitory effect of calcium channels of Nigella sativa on guinea pig tracheal chains. To investigate the other mechanism responsible for the relaxant effect of this plant, the stimulatory effect of Nigella sativa on ß 2 -adrenergic receptors in tracheal chains of the guinea pig was...

background: amoebiasis is due to infection with the protozoan parasite entamoeba histolytica. the patients infected with e. histolytica must be treated right after definite diagnosis and no need to treat infected individuals with e. dispar isolates. metronidazole is used as a drug of choice against amoebiasis. however, like a lot of other chemical agents, this drug has its own side effects. thi...

Watary extract of ALLIUM SATIVUM when administered Intravenously (I.V.) to NORMOTENSIVE dogs, produced a significant fall in their mean blood pressure. This effect was not antagonized by atropine or antihistamines. The extract increased the activity of Isolated Guinea Pig Ileum preparation. This effect of A Sativum was blocked by Diamentane (JPMA 31:12, 1981).