In the recent work, the reaction mechanism between triphenylphosphine 1, dialkyl acetylenedicarboxylates 2 in the presence of NH-acid, such as 5-aminoindazole 3 were investigated theoretically. Quantum mechanical studies were performed for evaluation of potential energy surfaces of all structures participated in the reaction mechanism both in gas phase and in dichloromethane. The first step of ...

The human parathyroid hormone (PTH) receptor (hPTH1R), containing a 9-amino acid sequence of rhodopsin at its C terminus, was transiently expressed in COS-7 cells and solubilized with 0.25% n-dodecyl maltoside. Approximately 18 microg of hPTH1R were purified to homogeneity per mg of crude membranes by single-step affinity chromatography using 1D4, a monoclonal antibody to a rhodopsin epitope. T...

The increasing interest in click chemistry and its use to stabilize turn structures led us to compare the propensity for β-turn stabilization of different analogs designed as mimics of the β-turn structure found in tendamistat. The β-turn conformation of linear β-amino acid-containing peptides and triazole-cyclized analogs were compared to 'conventional' lactam- and disulfide-bridged hexapeptid...

Introduction Conclusions References Tables Figures Back Close Full Screen / Esc This discussion paper is/has been under review for the journal Atmospheric Chemistry and Physics (ACP). Please refer to the corresponding final paper in ACP if available. Abstract Introduction Conclusions References Tables Figures Back Close Full Screen / Esc Abstract Effect of the exclusion of crustal ions (Ca 2+ ,...

The 7S and 11S seed storage proteins from four perennials related to soybean (Glycine canescens, G. tomentella, G. tabacina, and G. clandestina) were analyzed by sodium dodecyl sulfate-gel electrophoresis. Each species yielded a unique electrophoretic pattern that varied in the total number of bands and their relative mobilities. In every case, the electrophoretic patterns were substantially di...

Vagal afferents play a role in gut-brain signaling of physiological and pathological stimuli. Here we investigated how backdiffusion of luminal HCl or NH 4 OH and pentagastrin-stimulated acid secretion interact in the communication between rat stomach and brainstem. Rats were pretreated intraperitoneally with vehicle or appropriate doses of cimetidine, omeprazole, pentagastrin, dexloxiglumide (...

Vagal afferents play a role in gut-brain signaling of physiological and pathological stimuli. Here, we investigated how backdiffusion of luminal HCl or NH(4)OH and pentagastrin-stimulated acid secretion interact in the communication between rat stomach and brain stem. Rats were pretreated intraperitoneally with vehicle or appropriate doses of cimetidine, omeprazole, pentagastrin, dexloxiglumide...

Cell-wall fractions were obtained from Aspergillus niger and Chaetomium globosum. Non-structural protein was removed by successive washes in urea, NH,OH and formic acid. Amino acid analyses indicated that structural wall proteins were acidic. Aspartic acid was the free amino terminal residue of the protein in both species. Comparison of the ‘maps’ of peptic peptides indicate that there may be s...

a factorial experiment based on completely randomized design (crd) was performed with three replications to investigate the interaction between salinity and nh+4 / no-3 ratio on olive saplings. four levels of salinity (0, 50, 100,150 mm) and different ratios of nh+4/ no-3 (0:14, 2:12, 4:10, 6:8) were applied on one-year old olive saplings grown in perlite: sand media (1:1). results indicated th...

SLC26A4 encodes pendrin, a transporter exchanging anions such as chloride, bicarbonate, and iodide. Loss of function mutations of SLC26A4 cause Pendred syndrome characterized by hearing loss and enlarged vestibular aqueducts as well as variable hypothyroidism and goiter. In the kidney, pendrin is expressed in the distal nephron and accomplishes HCO(3)(-) secretion and Cl(-) reabsorption. Renal ...