نتایج جستجو برای: nf kappa b

تعداد نتایج: 954140  

Journal: :Molecular cell 1998
S Kasibhatla T Brunner L Genestier F Echeverri A Mahboubi D R Green

Apoptosis induced by DNA damage and other stresses can proceed via expression of Fas ligand (FasL) and ligation of its receptor, Fas (CD95). We report that activation of the two transcription factors NF-kappa B and AP-1 is crucially involved in FasL expression induced by etoposide, teniposide, and UV irradiation. A nondegradable mutant of I kappa B blocked both FasL expression and apoptosis ind...

Journal: :Research in virology 1991
G E Griffin K Leung T M Folks S Kunkel G J Nabel

Cells of the monocyte-macrophage lineage are important targets of HIV infection. We report here that the phenotypic differentiation of monocyte cell lines induced by phorbol esters or tumour necrosis factor alpha (TNF alpha) is associated with expression of nuclear factor kappa B (NF-kappa B). In parallel with such differentiation, HIV transcription, monitored using an HIV long terminal repeat ...

Journal: :Molecular pharmacology 1998
Z Nie Y Mei M Ford L Rybak A Marcuzzi H Ren G L Stiles V Ramkumar

The A1 adenosine receptor (A1AR) contributes to the cytoprotective action of adenosine under conditions known to generate reactive oxygen species (ROS). Pharmacological manipulation of A1AR expression has been shown to modulate this cytoprotective role. In this study, we provide evidence that ROS generated could increase the expression of the A1AR and thereby offset the detrimental effects of R...

Journal: :Folia Pharmacologica Japonica 2001

2016
Michel Leclerc Nicolas Kresdorn Ralf Horres

In the present paper we show a survey of the Asterias rubens sea star genome for genes associated with NF-kappa-B proteins implied in the immune response. The NF-kappa B gene, into 2 subunits, was found in this invertebrate.

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