A new approach to inferring the mass composition of cosmic rays at energies above 10 Abstract We describe a new approach to establishing the mass composition at high energies. Based on measuring both the vertical and inclined shower rates, it has the potential to distinguish heavy nuclei from light nuclei. We apply the method to Haverah Park data above 10 18 eV to show that, under the assumptio...

A new approach to inferring the mass composition of cosmic rays at energies above 10 Abstract We describe a new approach to establishing the mass composition at high energies. Based on measuring both the vertical and inclined shower rates, it has the potential to distinguish heavy nuclei from light nuclei. We apply the method to Haverah Park data above 10 18 eV to show that, under the assumptio...

Urease is an important enzyme both in agriculture and medicine research. Strategies based on urease inhibition is critically considered as the first line treatment of infections caused by urease producing bacteria. Since, urease possess agro-chemical and medicinal importance, thus, it is necessary to search for the novel compounds capable of inhibiting this enzyme. Several computational methods...

With the discovery of evidence for neutrino mass, a vivid gamma ray sky at multi-TeV energies, and cosmic ray particles with unexpectedly high energies, astroparticle physics currently runs through an era of rapid progress and moving frontiers. The non-vanishing neutrino mass establishes one smooth component of dark matter which does not, however, supply a critical mass to the Universe. Other d...

We present a new hybrid meta exchange-correlation functional, called M05-2X, for thermochemistry, thermochemical kinetics, and noncovalent interactions. We also provide a full discussion of the new M05 functional, previously presented in a short communication. The M05 functional was parametrized including both metals and nonmetals, whereas M05-2X is a high-nonlocality functional with double the...

Molecular mechanics with generalised Born and surface area solvation (MM/GBSA) is a popular method to calculate the free energy of the binding of ligands to proteins. It involves molecular dynamics (MD) simulations with an explicit solvent of the protein-ligand complex to give a set of snapshots for which energies are calculated with an implicit solvent. This change in the solvation method (exp...

Solvation free energy is a fundamental thermodynamic quantity that should be determined to estimate various physicochemical properties of a molecule and the desolvation cost for its binding to macromolecular receptors. Here, we propose a new solvation free energy function through the improvement of the solvent-contact model, and test its applicability in estimating the solvation free energies o...

according to ipcc report 2013, the role of man in environmental catastrophe is incontrovertible because of high greenhouse emission in now and recent century. buildings nearly discharge one third of these pollutants and the task of architects to prevent this hazardous procedure is critical. in the other hand, one main basis of sustainability is education due to preserve environment and then, tr...