The paper addresses robustness of complete stability with respect to perturbations of the interconnections of nominal symmetric neural networks. The influence of the maximum neuron activation gain on complete stability robustness is discussed for a class of third-order neural networks. It is shown that high values of the gain lead to an extremely small complete stability margin of all nominal s...

We describe an accelerated hardware neuron being capable of emulating the adaptive exponential integrate-and-fire neuron model. Firing patterns of the membrane stimulated by a step current are analyzed in transistor level simulations and in silicon on a prototype chip. The neuron is destined to be the hardware neuron of a highly integrated wafer-scale system reaching out for new computational p...

The anterior burster (AB) neuron of the lobster stomatogastric ganglion displays varied rhythmic behavior when treated with neuromodulators and channel-blocking toxins. We introduce a channel-based model for this neuron and show how bifurcation analysis can be used to investigate the response of this model to changes of its parameters. Two dimensional maps of the parameter space of the model we...

delayed neuronal death after seizure attack may be mediated by the induction of apoptosis-pathway. caspase-3, a mammalian cysteine protease, promotes apoptosis after some neurological disorders. neuron regeneration peptides (nrps) are small synthetic peptides that stimulate neural proliferation, migration, and differentiation with no apparent toxicity and high target specificity in cns. in the ...

in this study organotypic adult spinal cord slices were used to investigate whether caspases could participate in the apoptosis of motor neurons. the thoracic region of spinal cord was sliced using a tissue chopper and cultured in a medium for 6h. morphological and biochemical features of apoptosis were assessed by fluorescent staining and terminal deoxynucleotidyl nick end labeling (tunel) met...

introduction: (s)- 3,5-dihydroxyphenylglycine (dhpg) is an agonist for group i metabotropic glutamate receptors. dhpg-induced synaptic depression of excitatory synapses on hippocampal pyramidal neurons is well known model for synaptic plasticity studies. the aim of the present study was to examine the effects of dhpg superfusion on excitatory synapses on pyramidal and fast-spiking gabaergic cel...

In this paper we present Hopfield model of a neuron dynamics given by the neuronic equation. In the first model second order neuronic equation describe the behavior of a neuron in the presence of some local positive feedback. The second model portray two neurons in which first order neuronic equation represents dynamics of the second neuron in the presence of a discharged pulse coded signal fun...

Analysis and characterization of neuronal discharge patterns are of interest to neurophysiologists and neuropharmacologists. In this paper we present a hidden Markov model approach to modeling single neuron electrical activity. Basically the model assumes that each interspike interval corresponds to one of several possible states of the neuron. Fitting the model to experimental series of inters...

A model is proposed in which the neuron serves as an information channel. Channel distortion occurs through the channel since the mapping from input Boolean codes to output codes are many-to-one in that neuron outputs consist of just two distinguished states. Within the described model, the neuron performs a decision-making function. Decisions are made regarding the validity of a question passi...

spinal muscular atrophy (sma) is a genetic disorder which affect nervous system and is characterized with progressive distal motor neuron weakness. the survival motor neuron (smn) protein level reduces in patients with sma. two different genes code survival motor neuron protein in human genome. skeletal and intercostal muscles denervation lead to weakness, hypotony, hyporeflexia, respiratory fa...