632 Incidence and prevalence of NMOSD in Australia and New Zealand W Bukhari, K M Prain, P Waters, M Woodhall, C M O’Gorman, L Clarke, R A Silvestrini, C S Bundell, D Abernethy, S Bhuta, S Blum, M Boggild, K Boundy, B J Brew, M Brown, W J Brownlee, H Butzkueven, W M Carroll, C Chen, A Coulthard, R C Dale, C Das, K Dear, M J Fabis-Pedrini, D Fulcher, D Gillis, S Hawke, R Heard, A P D Henderson, ...

MATERIALS AND METHODS < A systematic search was conducted of the relevant published evidence from Embase, MEDLINE, and Cochrane < Search limits were articles in English and human < Retrieved citations were screened by two independent reviewers according to inclusion criteria: < Population: NMO patients with any age Interventions: Any interventions for treatment for NMO < Outcomes: Incidence and...

S. Bará Area de Optica, E.U., Optica e Optometria, Universidade de Santiago de Compostela, 15782 Santiago de Compostela, GALIZA Spain A. Ciro López Grupo de Optica y Fotonica, Instituto de Fisica, Universidad de Antioquia, A.A1226, Medellin, Colombia Facultad de Ciencias, Instituto Tecnologico Metropolitano, calle 73 #76A-354, Medellin, Colombia Z. Jaroszewicz [email protected] Institute ...

Objective To describe the characteristics of 34 Brazilian NMO patients. To evaluate the contribution of the 2015 criteria to the diagnosis of NMO spectrum disorders (NMOSD) in 40 patients with longitudinal extensive transverse myelitis (LEMT). Methods This is a retrospective, descriptive and analytic study. Results Among NMO patients, there was a predominance of women, with onset in the fou...

Karpakam, a female Hindu child of 7 years, was admitted into the Madras General Hospital, under Lieut.-Colonel McRobert, i.m.s., on the 23rd November, 1939. The complaint was blindness and inability to use the lower limbs. There had been no previous illnesses of note, the family history was negative and the dietary habits similar to those of her class, i.e., non-vegetarian. The child had been a...

We used two methods to estimate short-wave (S) cone spectral sensitivity. Firstly, we measured S-cone thresholds centrally and peripherally in five trichromats, and in three blue-cone monochromats, who lack functioning middle-wave (M) and long-wave (L) cones. Secondly, we analyzed standard color-matching data. Both methods yielded equivalent results, on the basis of which we propose new S-cone ...

Neuromyelitis optica (NMO) is an idiopathic inflammatory disorder of the central nervous system (CNS) that preferentially affects the optic nerves and spinal cord. In Asia, NMO has long been considered a subtype of multiple sclerosis (MS). However, recent clinical, pathological, immunological, and imaging studies have suggested that NMO is distinct from MS. This reconsideration of NMO was initi...

Neuromyelitis optica (NMO) is an inflammatory autoimmune disorder of the CNS that predominantly affects the spinal cord and optic nerves. A majority (approximately 75%) of patients with NMO are seropositive for autoantibodies against the astrocyte water channel aquaporin-4 (AQP4). These autoantibodies are predominantly IgG1, and considerable evidence supports their pathogenicity, presumably by ...

Central or peripheral demyelinating disorders including neuromyelitis optica, isolated optic neuritis or myelitis, and Guillain-Barre syndrome (GBS) in patients with tuberculosis have been well documented in the literature. , 2 It has been suggested that they are most likely due to an immune reaction to tuberculosis rather than due to direct invasion of tuberculosis or the adverse effect of ant...

Patients with neuromyelitis optica spectrum disorder (NMOSD) typically manifest recurrent episodes of optic neuritis (ON) and myelitis. Recently revised diagnostic criteria do not restrict the diagnosis of NMOSD to patients associated with elevation of anti–aquaporin 4 antibody (AQP4Ab), capable of causing destruction of astrocytes expressing AQP4. If compatible clinical and radiologic features...