نتایج جستجو برای: neurological soft signs

تعداد نتایج: 288502  

Journal: :Schizophrenia bulletin 2004
Mrigendra Das Veena Kumari William Soni Ulrich Ettinger Brendan Binneman Catherine Hughes Ravi Mehrotra Tonmoy Sharma

Neurological soft signs (NSS) are nonspecific indicators of brain dysfunction that are found to be in excess and correlated with cognitive dysfunction and psychopathology in patients with schizophrenia. The aim of the study was to examine whether the severity of NSS determines the efficacy of atypical antipsychotics in schizophrenia. Forty-three patients with schizophrenia were assessed on psyc...

2017
Liliana Galindo Daniel Bergé Graham K. Murray Anna Mané Antonio Bulbena Victor Pérez Oscar Vilarroya

Brain connectivity and neurological soft signs (NSS) are reportedly abnormal in schizophrenia and unaffected relatives, suggesting they might be useful neurobiological markers of the illness. NSS are discrete sensorimotor impairments thought to correspond to deviant brain development. Although NSS support the hypothesis that schizophrenia involves disruption in functional circuits involving sev...

Journal: :PeerJ 2016
Liliana Galindo Francisco Pastoriza Daniel Bergé Anna Mané Marisol Picado Antonio Bulbena Patricia Robledo Victor Pérez Oscar Vilarroya Claude Robert Cloninger

The heritability of schizophrenia and most personality traits has been well established, but the role of personality in susceptibility to schizophrenia remains uncertain. The aim of this study was to test for an association between personality traits and Neurological Soft Signs (NSS), a well-known biological marker of schizophrenia, in non-psychotic relatives of patients with schizophrenia. For...

2014
Dusan Hirjak Robert Christian Wolf Sabine C. Koch Laura Mehl Janna K. Kelbel Katharina Maria Kubera Tanja Traeger Thomas Fuchs Philipp Arthur Thomann

BACKGROUND Neurological abnormalities including a variety of subtle deficits such as discrete impairments in sensory integration, motor coordination (MOCO), and sequencing of complex motor acts are frequently found in patients with schizophrenia (SZ) and commonly referred to as neurological soft signs (NSS). Asperger-syndrome (AS) is characterized by sensory-motor difficulties as well. However,...

Journal: :Psychiatry research 2015
Michael T Compton Francisco Fantes Claire Ramsay Wan Stephanie Johnson Elaine F Walker

Motor abnormalities represent a neurobehavioral domain of signs intrinsic to schizophrenia-spectrum disorders, though they are commonly attributed to medication side effects and remain understudied. Individuals with first-episode psychosis represent an ideal group to study innate movement disorders due to minimal prior antipsychotic exposure. We measured dyskinesias, stereotypies, and catatonic...

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