BACKGROUND Proton magnetic resonance imaging (MRS) is used increasingly to image the spinal cord in compressive cervical myelopathy (CSM). However, detailed analyses of the underlying histomorphological changes leading to MRS alterations are still lacking. The aim of our study was to correlate neuroimaging and neuropathologic alterations in a rabbit myelopathy model. METHODS Chronic spinal co...

Vertebral hemangiomas are benign vascular lesions of bone , composed multiple thin-walled vessels surrounded by fat infiltrating the medullary cavity between bony trabeculae.(1) Hemangiomas account for around 2-3% all spinal tumors and only 0.9-1.2% these symptomatic. Surgery is recommended if they progress rapidly cause neurological deficits. 47 years old female patient presented with bilatera...

Neuro-Behçet disease (NBD) is a multisystem inflammatory disorder characterized by oral lesions, genital lesions, uveitis, and neurological deficits. If left untreated, it may lead to worsening neurological function and can be fatal. Here we present a case of a 52-year-old woman who was diagnosed with Behçet disease (BD) as a teenager and had a relatively mild disease course. Decades later afte...

Immunotherapy has emerged as a powerful therapeutic approach in many areas of clinical oncology and hematology. The approval ipilimumab, monoclonal antibody targeting the immune cell receptor CTLA-4, marked beginning era checkpoint inhibitors. In meantime, numerous antibodies PD-1 pathway have expanded class clinically approved Furthermore, novel directed against other checkpoints are currently...