intermediateand high-grade tumors; (iii) the term ‘tumor’ (neuroendocrine tumor, NET) is meant for lowto intermediate-grade neoplasms, as previously defined either ‘carcinoid’ or ‘atypical carcinoid’; (iv) the word ‘carcinoma’ (neuroendocrine carcinoma, NEC) is meant only for high-grade neoplasms, as previously defined poorly differentiated carcinomas. This terminology is adopted by the ENETS 2...

PATIENT Female, 45 FINAL DIAGNOSIS: Neuroendocrine tumor Symptoms: Abdominal pain Medication: - Clinical Procedure: - Specialty: Gastroenterology and Hepatology. OBJECTIVE Unusual setting of medical care. BACKGROUND Neuroendocrine tumor of the ampulla of Vater is extremely rare and is generally a low-grade endocrine cell tumor. The merits of radical vs. local resection remain uncertain. C...

Neuroendocrine tumors of the gastroenteropancreatic tract remain a difficult array of neoplasia to treat. Treatment of advanced and metastatic gastroenteropancreatic neuroendocrine tumors has traditionally been difficult with few systemic treatment options. In 2011, two new targeted therapies, everolimus and sunitinib were approved for treatment of pancreatic neuroendocrine tumor. The approval ...

Neuroendocrine tumors are unique and rare tumors originating from neuroendocrine cells. Large cell neuroendocrine tumors have been found in almost every organ such as gastrointestinal tract, bronchopulmonary, pancreas, uterine cervix, urinary bladder and salivary gland, but primary sites in gastrointestinal tract and lung are the most frequent. These neoplasms show neuroendocrine differentiatio...

1. Incipient neuroendocrine neoplasia: Dysplasia/Tis 2. True neuroendocrine tumors a. Well differentiated NETs (carcinoids, pancreatic neuroendocrine neoplasms) b. High-grade neuorendocrine carcinoma 3. Hybrid tumors a. Mixed tumors i. Mixed adenocarcinoma-neuorendocrine carcinoma ii. Mixed neuorendocrine tumor and non-neuroendocrine carcinoma iii. Duodenal gangliocytic paraganglioma b. Inciden...

Background: Certain marker studies have practical importance in the biology of prostate cancer. The purpose of this study was to determine whether the quantification of certain neuroendocrine and proliferative markers obtained during transurethral resection or prostatectomy, would help in the prognostic evaluation of prostatic adenocarcinomas. Methods: The present study was performed on samples...

background: certain marker studies have practical importance in the biology of prostate cancer. the purpose of this study was to determine whether the quantification of certain neuroendocrine and proliferative markers obtained during transurethral resection or prostatectomy, would help in the prognostic evaluation of prostatic adenocarcinomas.   methods: the present study was performed on sampl...

Rectal neuroendocrine carcinoma is rare with poor prognosis. We report herein a case of advanced moderately differentiated neuroendocrine carcinoma of the rectum with relatively favorable prognosis treated by postoperative adjuvant chemoradiation therapy. A 58-year-old Japanese female was referred and colonofiberscopy revealed an easybleeding irregular tumor in the lower rectum, which was patho...

A bronchial carcinoid tumor is a rare pulmonary neuroendocrine tumor. This report describes case where patient experienced multiple episodes of hemoptysis and dyspnea on exertion over the course five months. An initial chest X-ray showed an elevated right hemidiaphragm with atelectasis, follow-up computed tomography (CT) scan was ordered to further assess this finding. The CT revealed occluding...

We report the case of a female patient who had a neuroendocrine tumor in the pancreatic tail. Followup using (68)Ga DOTA-d-Phe(1)-Tyr(3)-octreotide (DOTATOC) positron-emission tomography (PET)/computed tomography (CT) detected a round, well-circumscribed nodular mass that exhibited positive somatostatin receptors. This finding was highly suggestive of an accessory spleen; however, due to the sl...