Topiramate was administered to eight patients with classical trigeminal neuralgia with or without previous symptomatic therapy with other antiepileptic drugs. The topiramate doses ranged from 50 to 100 mg a day, according to the clinical response and the reported side effects. Three patients had complete symptoms remission, three reported moderate improvement, and the treatment was not effectiv...

S uperior laryngeal neuralgia is described as a rare disorder characterized by severe pain in the lateral aspect of the throat, submandibular region, and underneath the ear, precipitated by swallowing, shouting, or turning the head. A trigger point is present on the lateral aspect of the throat overlying the thyrohyoid membrane. The etiology of superior laryngeal neuralgia is unclear, although ...

Trigeminal neuralgia(TN) is a severe unilateral paroxys¬mal facial pain that causes intense distress and often compromises the quality of life of the patient. The aetiology and pathophysiology of TN is still not clear. Numerous treatment options for TN are available. Medical therapy is the first choice and surgical modalities are used only when medical therapy fails. The challenge lies in asses...

A 21 year old man with severe osteogenesis imperfecta developed classic right maxillary trigeminal neuralgia. Brain imaging showed pronounced basilar invagination, which was probably responsible for the pain through distortion of the trigeminal sensory root secondary to displacement of the brainstem. Osteogenesis imperfecta may be added to Paget's disease as a potential cause of symptomatic tri...

Authors' objectives The objective of this technology review was to assess the efficacy of gamma knife stereotactic radiosurgery (SRS) in the treatment of arteriovenous malformations, acoustic neuroma, cerebral metastases and trigeminal neuralgia, the latter representing a non-invasive approach to precision ablation for benign conditions. The efficacy of gamma knife relative to microsurgery and ...

background: we aimed to study the curative effects of botulinum a toxin (btx-a) on the treatment of post-herpetic neuralgia (pnh). methods: we enrolled 58 pnh patients and treated them with hypodermic injection of btx-a in xiangyang no.1 people’s hospital, hubei university of medicine, hubei, china. we measured and compared the visual analog score (vas), neuropathy pain scale (nps), quality of ...

Eleven patients with intractable trigeminal neuralgia were treated by posterior fossa microvascular decompression. Complete pain relief was achieved in 7 patients (63.3%). Partial relief of symptoms was noted in 3 patients (27%). There was no operative mortality. Two patients developed transient lower cranial nerve palsies whereas one patient developed a CSF leak, requiring treatment by lumbar ...

Trigeminal neuralgia is a relatively common neuropathic pain which characterized by paroxysmal, sharp, shooting, shocking or piercing pain. The pain significantly affects the quality of life of patient. Various treatments extending from medical to neurosurgical procedures are available. Each treatment has its own advantages and disadvantages. The aim of this paper is to present various aspects ...

Pain typically accompanies acute herpes zoster and, in a proportion of patients, it persists well beyond rash healing. Pain must therefore be analyzed in trials of antiviral agents in herpes zoster, but different methods have been used to analyze pain in recent published trials. These reports are reviewed and their methodological strengths and weaknesses examined. Based on this review, recommen...

INTRODUCTION Intramedullary cavernous angioma (ICA) is a rare lesion of the spinal cord, representing only 3% - 5% of central nervous system lesions. The coexistence of trigeminal neuralgia and refractory itch is very rarely encountered in clinical practice. To our knowledge, a report of an ICA with trigeminal neuralgia and local neuropathic itch has never been published to date. Thus, we prese...