Dexamethasone is currently used for the treatment of peripheral nerve injury, but its mechanisms of action are not completely understood. Inflammation/immune response at the site of nerve lesion is known to be an essential trigger of the pathological changes that have a critical impact on nerve repair and regeneration. In this study, we observed the effects of various doses of dexamethasone on ...

OBJECTIVE To establish whether daily mechanical stimulation improves functional recovery of whisking after facial nerve transection injury and repair in rats. METHODS Forty rats underwent facial nerve transection injury and repair and subsequent quantitative facial movement testing. Animals were randomized into 2 experimental groups (n = 20 each). Both groups received daily 5-minute manual st...

Simultaneous shoulder and elbow dislocation is an uncommon condition, with only about ten cases reported in the literature. It also called bipolar humeral or floating humerus. Nerve involvement sometimes associated but radial nerve impairment yet to be described. We report a case of humerus occurring on young 22 years old. Non-surgical treatment was undertaken reduction followed by under genera...

Anterior interosseous nerve palsy subsequent to proximal humerus fracture is rare compared with an axillary nerve injury. This article presents a case of anterior interosseous nerve palsy secondary to such a fracture in an 87-year-old woman after a simple fall onto her outstretched hand. The patient had no sensory involvement but was unable to form an O with her thumb and index finger. She had ...

Evaluation of functional and structural recovery after peripheral nerve injury is crucial to determine the therapeutic effect of a nerve repair strategy. In the present study, we examined the relationship between the structural evaluation of regeneration by means of retrograde tracing and the functional analysis of toe spreading. Two standardized rat sciatic nerve injury models were used to add...

INTRODUCTION The rat median nerve injury and repair model gets increasingly important for research on novel bioartificial nerve grafts. It allows follow-up evaluation of the recovery of the forepaw functional ability with several sensitive techniques. The reflex-based grasping test, the skilled forelimb reaching staircase test, as well as electrodiagnostic recordings have been described useful ...

In this paper a continuous wave (cw) spectrometer in the far infrared range covering frequencies between several tens Gigahertz and one Terahertz is presented. The spectrometer employed a coherent detection scheme and therefore measures both the amplitude and phase of THz radiation. First spectroscopic results of Si-wafer and a test Bragg structure are presented.

Although peripheral nerve injury may result in a loss of function in innervated areas, the most effective method for nerve regeneration remains to be determined. The aim of the present study was to investigate the effect of control-released basic fibroblast growth factor (bFGF)-loaded poly-lactic-co-glycolic acid (PLGA) microspheres on sciatic nerve regeneration following injury in rats. bFGF-P...