PURPOSE To investigate the relationship between optical coherence tomography (OCT) and scanning laser polarimetry (SLP) in measuring peripapillary retinal nerve fiber layer (RNFL) thickness in glaucomatous eyes. METHODS Fifty glaucomatous eyes were evaluated in this study. Evaluations were analyzed two ways. First, parameters of the Stratus OCT (average thickness, superior/inferior average) a...

OBJECTIVE To quantitatively assess and compare the thickness of the retinal nerve fiber layer (RNFL) in ocular hypertensive eyes with normal and glaucomatous eyes using the Optical Coherence Tomograph (OCT 2000, software version A4X1; Humphrey Instruments, San Leandro, Calif). METHODS The mean RNFL thickness of ocular hypertensive (n = 28) eyes was compared with age-matched normal (n = 30) an...

Aim of work To evaluate the effect of refractive status and axial length of the eye on retinal nerve fiber layer (RNFL) thickness. Method A t tal of 116 eyes 62 subjects were enroll d in the study. RNFL thickness was measured using TOPCON 3D OCT 2000. Results Hyperopic group, as compared to normal, did not show any significant thickening for average, superior, inferior, nasal, and temporal quad...

Amyotrophic Lateral Sclerosis (ALS) is a complex neurodegenerative disorder that may have anterior visual pathway involvement. In this study, we compare the macular structure of patients with ALS to healthy controls, and examine correlations between macular sub-layer thickness measurements and pulmonary function tests and disease duration. ALS patients underwent optical coherence tomography (OC...

PURPOSE To examine characteristics of ocular hypertensive subjects and potential associations with estimated cerebrospinal fluid pressure (estCSFP). METHODS The population-based Beijing Eye Study 2011 included 3468 individuals with a mean age of 64.6±9.8 years. Ocular hypertension was defined as intraocular pressure (IOP) >21 mmHg, normal optic nerve head appearance and normal retinal nerve f...

In the present study, the effects of hyaluronic acid (HA) combined with chitosan conduit on peripheral nerve scarring and regeneration were investigated in a rat model of peripheral nerve crush injury. A total of 60 Sprague-Dawley rats were randomly distributed into four groups (15 rats in each group), in which the nerve was either not treated (control group) or treated with chitosan conduit, h...

OBJECTIVE To identify if anisometropic amblyopia is associated with changes in optic disk morphology. METHODS The study comprised a total of 80 eyes recruited from Shifa Foundation Community Health Centre and the Pakistan Institute of Medical Sciences, Islamabad between May and October 2012. Anisometropic amblyopia was the only cause of disability (visual acuity > or = 6/12) in amblyopic eyes...

OBJECTIVE To study how customizing the peripapillary scan diameter on the basis of optic nerve head (ONH) diameter affects retinal nerve fiber layer (RNFL) thickness measurements using Stratus optical coherence tomography (OCT). METHODS Retinal nerve fiber layer was examined using 1 fixed-diameter circular scan (3.4 mm) and 2 customized-diameter scans (at 0.5 mm and 1 mm from the ONH edge) in...

BACKGROUND Autosomal dominant spinocerebellar ataxia type 1 is an adult onset progressive disorder with well characterized neurodegeneration in the cerebellum and brainstem. Beyond brain atrophy, few data exist concerning retinal and optic nerve involvement. OBJECTIVE To evaluate retinal changes in SCA1 patients compared to age and gender matched healthy controls. METHODOLOGY/PRINCIPAL FIND...

PURPOSE To compare the performance of scanning laser topography (SLT) and scanning laser polarimetry (SLP) on the rim of the optic nerve head and its surrounding area and thereby to evaluate whether these imaging technologies are influenced by other factors beyond the thickness of the retinal nerve fiber layer (RNFL). MATERIALS AND METHODOLOGY A total of 154 eyes from 5 different groups were ...