conclusions our findings indicate that umbelliprenin exhibits concentration-dependent inhibitory effects on various cell types; it is potentially toxic against the ht29, ct26, mcf-7, 4t1, a172, and gl26 cell lines, potentially harmful against bmdscs, and non-toxic against pbmcs. therefore, if our results are approved in the future, umbelliprenin can be an appropriate candidate for developing tr...

In this study demographic, clinical, paraclinical, microbiological, and therapeutic features of patients with community-acquired acute bacterial meningitis admitted to a referral center for infectious diseases in Iran, have been evaluated. Medical records of adult (> 18 years) individuals with confirmed diagnosis of community-acquired bacterial meningitis during a 4-year period were retrospecti...

Natural focal infections with transmissible transmission caused by viruses of West Nile Fever, Batai, Inco, Sindbis, Tyagin are registered in various territories Russia, the form sporadic cases, characterized polymorphism clinical symptoms, from inapparent forms to severe, occurring Central nervous system damage (meningitis, meningoencephalitis), which complicates timely diagnosis and treatment...

Introduction: The early presentation of bacterial meningitis and aseptic are similar however treatment outcome different. Bacterial Meningitis Score helps to differentiate from meningitis.
 Aims: To evaluate score as clinical prediction rule in children with acute Methods: This was a hospital based prospective study done at pediatric department Nepalgunj Medical College, Nepalgunj, tertiar...

Background and Aim: Post-neurosurgical meningitis can lead to severe complications and high mortality rates. The incidence varies in different conditions. The aim of this retrospective study is to determine the risk factors, occurrence, and microbiological spectrum of meningitis in patients with non-emergency craniotomy. Methods and Materials/Patients: The patients who underwent non-emergency ...

Background: Enterovirus (EV) infections are one of the most common causes of aseptic meningitis in pediatrics. To diagnose EV meningitis, virus isolation in cell cultures is often time consuming and lacks sensitivity to be of clinical relevance. This makes the virus culture results difficult to interpret. The rapid detection of EVs in cerebrospinal fluid (CSF) by molecular diagnostic techniques...

Leptomeningeal carcinomatosis, known by a variety of names, including leptomeningeal metastases and neoplastic meningitis, indicates spread of tumor to the cerebrospinal fluid (CSF) and invasion of the subarachnoid space. The term leptomeningeal (from the Greek lepto, meaning “fine” or “slight”) describes the thin meninges, the arachnoid and the pia mater, between which the CSF is located. Alth...