Umbilical metastasis is one of the main characteristic signs of extensive neoplastic disease and is universally referred to as Sister Mary Joseph's nodule. It indicates neoplasm of inner organs mostly located in the gastrointestinal tract or the pelvis. However, in approximately 15-30% the primary tumor remains occult. In most cases, Sister Mary Joseph's nodule appears as an early and sometimes...

PURPOSE Natural killer (NK) cell neoplasm is a rare disease that follows an acute course and has a poor prognosis. It usually emerges from the nose and appears in the ocular tissue as a metastasis. Herein, we describe a case of NK-cell neoplasm in which the eye was considered to be the primary organ. CASE A 50-year-old female displayed bilateral anterior chamber cells, vitreous opacity, bullo...

Abstract Introduction Chondroblastoma is a rare, benign locally but aggressive bone tumor. It accounts for < 1% of primary bony tumors, and mostly arises from long bones; the rib chondroblastoma especial rare. Due to its rarity, there are no definitive or standard treatment guidelines. Case presentation A case 24-year-old male with located on 6th posterior left rib. Computed tomography (CT) ...

Introduction: Salivary gland tumors (SGTs) are important parts of human neoplasms. The most common SGT is pleomorphic adenoma and the most common malignant SGTs are mucoepidermoid carcinoma and adenoid cystic carcinoma (ACC). Metastasis-associated genes 1 (MTA1), a member of the nucleosome remodeling and histone deacetylation complex, is one newly discovered gene which recruits histone deacetyl...

Amelanotic melanoma is an atypical that presents without pigmentation and can thus be misdiagnosed as benign neoplasm. Ungual trauma induce amelanotic of the fingernail well pyogenic granuloma (PG). We present case a patient in his 60s with PG-like lesion on third nail plate was preceded by ungual one year ago. A shave biopsy revealed ulcerated nodule composed epitheloid cells melanocytic atypi...