PURPOSE To study the expression of HER2, p53 and Ki67 proteins in cystoplasties. METHODS Sixty rats were distributed randomly into three groups of 20 animals. Bladder augmentation was held to increase with ileum (Group I), colon (Group II) and stomach (Group III). Tissue samples of neobladder was collected from each rat to its own control. The animals were sacrificed after 12 weeks. The neobl...

OBJECTIVES In select female patients, bladder reconstruction following cystectomy will provide a better quality of life and self-image. We reviewed our results with ileocolonic orthotopic neobladders in female patients undergoing cystectomy for bladder cancer. Impact of pathologic stage on disease outcome, urinary continence results and surgical technique are described. Because of the relative ...

PURPOSE We describe the functional outcome on erectile function, continence and voiding, and local and distant cancer recurrence rates in 44 patients after sexuality preserving cystectomy and neobladder (prostate sparing cystectomy). MATERIALS AND METHODS A total of 44 males underwent cystectomy with preservation of the prostate, seminal vesicles and vasa deferentia, after which a Studer type...

The present study aimed to report the urodynamic data from 46 male patients who underwent an orthotopic N-shaped neobladder replacement following a radical cystectomy during a 12-month period and to provide urodynamic evidence for the improvement of this technique. A total of 46 consecutive male patients underwent a radical cystectomy and orthotopic N-shaped neobladder substitution due to muscl...

PURPOSE Radical cystectomy and urinary diversion are the standard treatment for invasive bladder cancer. We analyzed the long-term (>10 years postoperatively) functional outcomes, complications, and urodynamic findings in a single center series of patients who underwent cystectomy and a Studer ileal neobladder substitution. MATERIALS AND METHODS A retrospective chart review of 108 Studer pouc...

BACKGROUND To identify symptom distress and clusters in patients 3 months after radical cystectomy and to explore their potential predictors. METHODS A cross-sectional design was used to investigate 99 bladder cancer patients 3 months after radical cystectomy. Data were collected by demographic and disease characteristic questionnaires, the symptom experience scale of the M.D. Anderson sympto...