We have developed a model of Ca(2+) handling in ferret ventricular myocytes. This model includes a novel L-type Ca(2+) channel, detailed intracellular Ca(2+) movements, and graded Ca(2+)-induced Ca(2+) release (CICR). The model successfully reproduces data from voltage-clamp experiments, including voltage- and time-dependent changes in intracellular Ca(2+) concentration ([Ca(2+)](i)), L-type Ca...

Given any connected, open 3-manifold U having finitely many ends, a non-compact 3-manifold M is constructed having the following properties: the interior of M is homeomorphic to U ; the boundary of M is the disjoint union of finitely many planes; M is not almost compact; M is eventually end-irreducible; there are no proper, incompressible embeddings of S ×R in M ; every compact subset of M is c...

let $g$ be a locally compact group, $h$ be a compact subgroup of $g$ and $varpi$ be a representation of the homogeneous space $g/h$ on a hilbert space $mathcal h$. for $psi in l^p(g/h), 1leq p leqinfty$, and an admissible wavelet $zeta$ for $varpi$, we define the localization operator $l_{psi,zeta} $ on $mathcal h$ and we show that it is a bounded operator. moreover, we prove that the localizat...

When equipped with the natural topology first defined by Chabauty, the closed subgroups of a locally compact group G form a compact space C(G). We analyse the structure of C(G) for some low-dimensional Lie groups, concentrating mostly on the 3-dimensional Heisenberg group H. We prove that C(H) is a 6-dimensional space that is path–connected but not locally connected. The lattices in H form a de...

In a previous paper [4] we obtained the Hopf algebra structure of k*(G ; Q(P» where G is a compact connectvd Lie group and Q(P) is the quotient ring of Z with respect to a multiplicative subset generated by a set of primes, such that H*(G ; Q(P)) is torsion free . Here we study the properties of the connective K-theory of the Lie groups Spin(n) . Since H*(Spin(n) ; Z) is torsion free if n _< 6,...

Total Variation or Bilateral Total variation based regularization of ill-posed Super Resolution (SR) problem is well-established. However, the SR image reconstructed by this method produces ringing artifacts near strong edges. Second, the extension of SR Imaging to SR video always desire faster SR reconstruction process. In this paper we develop a gain-controlled based locally adaptive regulari...

Let L be a big line bundle on a compact complex manifold X. Given a non-pluripolar compact subset K of X and the weight φ of a continuous Hermitian metric e on L, we define the energy at equilibrium of (K,φ) as the Aubin-Mabuchi energy of the extremal psh weight associated to (K,φ). We prove the differentiability of the energy at equilibrium with respect to φ, and we show that this energy descr...

To investigate the cellular mechanisms for altered Ca homeostasis and contractility in cardiac hypertrophy, we measured whole-cell L-type Ca currents (ICa,L), whole-cell Ca 21 transients ([Ca]i), and Ca 21 sparks in ventricular cells from 6-month-old spontaneously hypertensive rats (SHRs) and from ageand sex-matched Wistar-Kyoto and Sprague-Dawley control rats. By echocardiography, SHR hearts h...

To investigate the cellular mechanisms for altered Ca2+ homeostasis and contractility in cardiac hypertrophy, we measured whole-cell L-type Ca2+ currents (ICa,L), whole-cell Ca2+ transients ([Ca2+]i), and Ca2+ sparks in ventricular cells from 6-month-old spontaneously hypertensive rats (SHRs) and from age- and sex-matched Wistar-Kyoto and Sprague-Dawley control rats. By echocardiography, SHR he...