Introduction: Gum Tragacanth (GT) obtained from Astragalus gossypinus is one of the most widely used natural gums which has found applications in many areas because of its attractive features such as biodegradability, nontoxic nature, natural availability, moisture absorption and creating a network of Hydrocolloid. It also has properties like maintenance and delivery of drugs, higher resistance...

The present investigation was designed to formulate a natural tablet for the treatment of vaginal candidiasis in order to eliminate side effects that are caused by existing antifungal drugs. Curcumin has promising antifungal activity in comparison with the existing azole antifungal drugs. Bioadhesive curcumin vaginal tablets were prepared by direct compression with different ratios of biadhesiv...

The natural and semisynthetic carbohydrates scleroglucan, locust bean gum, tamarind gum (glyloid) and its three sulphate derivatives (GP4311, GP4327 and GP4324), glycogen and its two sulphate derivatives (GP4427 and GP4435), alginic acid and dextran sulphate, were investigated for their inhibitory effect on rubella virus (RV) infection of Vero cells. The neutral polymer scleroglucan and two hig...

In this study, an ion-activated ketotifen ophthalmic delivery system was developed by using a natural polysaccharide, deacetylase gellan gum. Its rheological characteristics, stability, in vitro gelation, release in vitro, and pharmacodynamic activity in vivo were investigated. The formulation had an optimum viscosity that will allow easy drop as a liquid, which then underwent a rapid sol-gel t...

The purpose of this study was to determine the antimicrobial activity of one prescription and two commercially available over-the-counter mouthrinses and positive and negative controls against bacteria commonly found in the oral cavity. The bacteria used in this study were Streptococcus mutans, Streptococcus sanguis and Actinomyces viscosus. Sterile discs which were treated with the mouthrinses...

The utilization of natural gum polysaccharides as the vehicle for drug delivery systems and other biomedical applications has increased in recent decades. Their biocompatibility, biodegradability, price are much cheaper than materials. It is also renewable available massive amounts, which main reasons its use pharmaceutical applications. Gum can be easily functionalized with polymers to enhance...

Two experiments re-examined whether chewing spearmint gum affects initial word learning and/or immediate recall for a word list. Both experiments failed to show effects of chewing gum at learning or recall, nor did they suggest that chewing gum produces a context-dependent memory effect. This was true when extraneous contextual cues at learning and recall were minimised (Experiment 2). Together...

Ofloxacin is a synthetic chemotherapeutic antibiotic used for treatment of a variety of bacterial infections, but therapy suffers from low patients' compliance due to its unpleasant taste. This study was aimed to develop taste masked microspheres of ofloxacin using Eudragit and to prepare orodispersible tablets of the formulated microspheres using natural superdisintegrant. Taste masking Eudrag...

In recent years worldwide interest has grown towards the development of mucoadhesive drug delivery systems. These systems are capable of adhering to body's mucosal surfaces for an extended period of time, releasing their drug content in a retarded manner. The use of biopolymers, and in particular phytopolymers, could provide a natural basis for the development of such systems. The aim of this s...

In recent years worldwide interest has grown towards the development of mucoadhesive drug delivery systems. These systems are capable of adhering to body's mucosal surfaces for an extended period of time, releasing their drug content in a retarded manner. The use of biopolymers, and in particular phytopolymers, could provide a natural basis for the development of such systems. The aim of this s...