نتایج جستجو برای: natural bioactive compound
تعداد نتایج: 626583 فیلتر نتایج به سال:
The present article describes a structurally novel natural product of the paulomycin family, designated as paulomycin G (1), obtained from the marine strain Micromonospora matsumotoense M-412, isolated from Cantabrian Sea sediments collected at 2000 m depth during an oceanographic expedition to the submarine Avilés Canyon. Paulomycin G is structurally unique since-to our knowledge-it is the fir...
Traditional medicines, including Chinese herbal formulations, can serve as the source of potential new drugs, and initial research focuses on the isolation of bioactive lead compound(s). The development of novel plant-derived natural products and their analogs for anticancer activity details efforts to synthesize new derivatives based on bioactivity- and mechanism of action-directed isolation a...
Here we report on a novel thiazole/oxazole-modified microcin (TOMM) from Bacillus amyloliquefaciens FZB42, a Gram-positive soil bacterium. This organism is well known for stimulating plant growth and biosynthesizing complex small molecules that suppress the growth of bacterial and fungal plant pathogens. Like microcin B17 and streptolysin S, the TOMM from B. amyloliquefaciens FZB42 undergoes ex...
Ergot alkaloids are nitrogen-containing natural products belonging to indole alkaloids. The best known producers are fungi of the phylum Ascomycota, e.g., Claviceps, Epichloë, Penicillium and Aspergillus species. According to their structures, ergot alkaloids can be divided into three groups: clavines, lysergic acid amides and peptides (ergopeptines). All of them share the first biosynthetic st...
This review describes bioactive natural products isolated from East African medicinal plants. It includes 211 bioactive compounds from 41 plant species, and cites 116 references.
Hinokitiol is a natural bioactive compound found in several aromatic and medicinal plants. It terpenoid synthetized secreted by different species as secondary metabolites. This volatile was tested explored for its biological properties. In this review, we report the pharmacological properties of hinokitiol focusing mainly on anticancer mechanisms. Indeed, it can block cell transformation at lev...
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