Introduction: Nasopharyngeal carcinoma (NPC) is a common cancer in the North-East region of India. Though the role of environmental contributors of NPC in the North-Eastern part of India is firmly established, EBV as an etiological agent in the region remains unexplored. Material and Methods: Fifty-one patients, who presented at the department of ENT, NEIGRIHMS and were confirmed as NPC upon h...

Nasopharyngeal cancer (NPC) is the 4th most common malignancy in Indonesia, after breast, cervical and lung cancer. The risk factors for this are Epstein-Barr virus, gender, race, adult age 30-50 years, family history, drinking alcohol smoking. prevalence of NPC Indonesia 6.2/100,000, with nearly 13,000 new cases, but a small proportion that has been documented. Adham et al (2012) reported head...

Asians and Pacific Islanders' (APIs) leading cause of death is cancer. We compared APIs' age-adjusted cancer mortality rates to other racial/ethnic groups and by API subgroup (i.e., Chinese, Koreans, Asian Indians, and Filipinos) using New York City (NYC) Mortality data and Census Bureau population estimates for 2001-2010. While other racial/ethnic groups' overall cancer mortality rates decline...

We read the paper of Valstar et al. [1] on discovery tubarial salivary glands with great interest. The authors discovered a pair previously overlooked, clinically relevant macroscopic glands. agree that these potentially may play an important role regard to efficient working and protection nasopharyngeal oropharyngeal mucosa, comparable saliva for oral cavity [2]. It is known treatment head nec...

BACKGROUND Nasopharyngeal carcinoma is often associated with neck lymph node (LN) metastases, which in many cases is the only manifestation of this disease. The submucosal and infiltrative characteristics of nasopharyngeal carcinoma make this type of cancer difficult to diagnose. Nasopharyngeal carcinoma has also been reported to be strongly associated with the Epstein-Barr virus. METHODS We ...

BACKGROUND The functional polymorphism rs4938723 in the promoter region of pri-miR-34b/c is potentially associated with susceptibility to several cancers, including hepatocellular carcinoma, colorectal cancer, and breast cancer. Here we conducted a comprehensive meta-analysis to investigate the association between rs4938723 and cancer risk. MATERIAL AND METHODS Eligible studies extracted from...

BACKGROUND Treatment of nasopharyngeal carcinoma requires the application of high dosages of radiation, leading to severe long-term complications in the majority of patients. Sensitizing tumor cells to radiation could be a means to increase the therapeutic window of radiation. Nasopharyngeal carcinoma cells display alterations in autophagy and blockade of autophagy has been shown to sensitize t...

Nasopharyngeal carcinoma is treated with radiotherapy and other modalities, but there is little information on individual genetic factors to help predict and improve patient outcomes. Single-nucleotide polymorphisms (SNP) in mature microRNA (miRNA) sequences have the potential to exert broad impact as miRNAs target many mRNAs. The aim of this study was to evaluate the effects of SNPs in mature ...

Nasopharyngeal carcinoma (NPC) is a malignant tumor that occurs in the wall of nasopharyngeal cavity and prevalent Southern China, Southeast Asia, North Africa, Middle East. According to studies, NPC one most common tumors Hainan, it has highest incidence rate among otorhinolaryngological malignancies. We proposed new deep learning network model improve segmentation accuracy target region cance...