We present a selective method for simultaneous determination of five polyether ionophores such as salinomycin (SAL), monensin (MON), narasin (NAR), semduramicin (SEM) and lasalocid (LAS) in aquatic samples using a liquid chromatography with one-step fluorescent derivatization of 2-(4-hydrazinocarbonyl-phenyl) 4,5-diphenylimidazole (HCPI) and 4-(4,5-diphenyl-1H-imidazol-2-yl) benzoyl chloride hy...

Nasal septum deviation (NSD) typically occurs following otorhinolaryngologic surgery. However, there is a lack of biomechanical parameters able to accurately evaluate the severity of NSD. The present study aimed to determine whether the deformation rate (DR) is associated with visual analogue scale (VAS) and nasal airway resistance (NAR), and to evaluate the application of DR measurements in na...

The conduct of clinical trials in colorectal cancer has historically relied upon endpoints such as disease-free (DFS) or overall survival (OS). While ideal, these endpoints require long-term follow-up, thus contributing to a slow pace of scientific progress in clinical research. Identification of short-term endpoints to serve as surrogates for DFS and OS would enable more rapid determination of...

Abstract Background Nasal nitric oxide (nNO), a noninvasive indicator for eosinophilic airway inflammation, has not been adequately studied in different types of rhinitis. The aim this study was to compare nNO levels between allergic (AR) and non-allergic rhinitis (NAR). Patients were included based on their chronic nasal symptoms. Total symptoms score (TNSS) evaluated. measured transnasally wi...

Early in their evolution, perhaps during their transition from Agnatha (jawless fish) to Gnathostomata (jawed animals), vertebrates committed as much as 1% of their proteinencoding genome to a new system of defense against parasites (1). Central to this anticipatory (adaptive) immune system (2) are three types of antigen receptor—immunoglobulin (Ig), T cell receptor (Tcr), and major histocompat...

BACKGROUND Remaining edema-free is a challenge for many automated peritoneal dialysis (APD) patients, especially those with fast ("high") transport characteristics. Although increased use of peritoneal dialysis (PD) solutions with high glucose concentrations may improve volume control, frequent use of such solutions is undesirable. METHODS We used the 3-pore kinetic model to evaluate 4 altern...

Background In the last years, studies have demonstrated that chronic rhinits is a common disorder in elderly patients, although epidemiologic data related to this population is sparing. Indeed, there is no information regarding the prevalence of rhinits in the elderly in Brazil. The aim of this study was to determine the prevalence, clinic features and severity of allergic rhinitis (AR) in the ...

Abstract Aims Appendicitis is the most common abdominal surgery emergency globally with 50,000 acute appendicectomies in UK annually. Despite improvements diagnostic techniques, negative still occur. We aimed to audit local results of appendicectomy rates (NAR) against 2012 National Appendicectomy Audit which recommends an NAR <20%. Methods Retrospective data patients who underwent from ...