the composite diazotization coupling reaction of sulfanilic acid and n, ndimethylaniline was used for the precise, accurate, and rapid determination of trace amounts of nitrite ion (0.02-3 µg/ml). the reaction was monitored spectrophotometrically by measuring the absorbance of the produced methyl orange at 510 nm by a fixed the method of 5.0 minutes. the relative standard deviation for the dete...

Introduction: The angiotensin 1-7 (Ang1-7) Mas receptor (MasR) axis, bradykinin (BK) and female sex hormone are involved in releasing of vasodilatory biomarkers including Nitric Oxide (NO). We examined the role of MasR and BK on NO metabolite (nitrite) production response to Ang 1-7 infusion in ovariectomized rats treated with estradiol. Methods: A total of 48 female Wistar rats were divided i...

McQuiston T. A. C. (1936) Poisoning with sodium nitrite. Lancet 2, 1153-1154. Polson C. J. & Tattersall R. N. (1969) Clinical Toxicology 2nd Ed, pp. 109-116. Pitman Medical, London. Shesser R., Mitchell J. & Edelstein S. (1981) Methaemoglobinaemia from isobutyl nitrite preparations. Annals of Emergency Medicine 10, 262-264. Walley T. & Flanagan M. (1987) Nitrite induced methaemoglobinaemia. Pos...

It has been suggested that nitrate and nitrite may play a role in the etiology of human oral cancer. We investigated whether salivary nitrate and nitrite and the activity of nitrate reductase (NRase) may affect the risk of oral cancer in Egypt, an area with high levels of environmental nitrosating agents. Levels of salivary nitrite (8.3 +/- 1.0 micrograms/ml) and nitrate (44 +/- 3.7 micrograms/...

BACKGROUND AND PURPOSE Hypoxic conditions favour the reduction of nitrite to nitric oxide (NO) to elicit vasodilatation, but the mechanism(s) responsible for bioconversion remains ill defined. In the present study, we assess the role of aldehyde dehydrogenase 2 (ALDH2) in nitrite bioactivation under normoxia and hypoxia in the rat and human vasculature. EXPERIMENTAL APPROACH The role of ALDH2...

The aim of this study was to obtain a nitrite-oxidizing bacterium with high nitrite oxidation activity for controlling nitrite levels. A nitrite-oxidizing bacterium, ZS-1, was isolated from the water of a coastal Pseudosciaena crocea-rearing pond. The strain was identified as Nitrobacter winogradskyi based on the phylogenetic analyses of the 16S ribosomal ribonucleic acid gene and nxrA sequence...

The nitrite anion is reduced to nitric oxide (NO*) as oxygen tension decreases. Whereas this pathway modulates hypoxic NO* signaling and mitochondrial respiration and limits myocardial infarction in mammalian species, the pathways to nitrite bioactivation remain uncertain. Studies suggest that hemoglobin and myoglobin may subserve a fundamental physiological function as hypoxia dependent nitrit...

Dementia is a common symptom of many degenerative brain diseases. The cholinesterase inhibitors are widely recommended for the treatment of Alzheimer’s disease and different kind of dementia to improve memory functions. Tacrine is the first drug from this group. Metrifonate has been used as an antihelminthic in tropical countries for more than 30 years, and even recently has been suggested as a...

Bacillus subtilis can use either nitrate or nitrite as a sole source of nitrogen. The isolation of the nasABCDEF genes of B. subtilis, which are required for nitrate/nitrite assimilation, is reported. The probable gene products include subunits of nitrate/nitrite reductases and an enzyme involved in the synthesis of siroheme, a cofactor for nitrite reductase.