INTRODUCTION Nail biopsy is thought to be a useful technique for the diagnosis of diseases affecting the nail apparatus and may help avoid delays in the diagnosis of important mucocutaneous diseases. Furthermore, it has therapeutic value in its own right. It is not a difficult technique to perform but it requires an in-depth knowledge of the anatomy and physiology of the nail unit, as well as s...

Damage to the supporting structures, disruption of the cementing substance binding the nail plate to the surrounding structures or formation of granular layer, which is otherwise absent in a normal nail bed and nail matrix, will produce onycholysis. Trauma from physical factors, manicuring, foreign body implantation or chemicals like solvents, various nail cosmetics and immersion in alkaline so...

Changes in severity of psoriasis and psoriatic arthritis (PsA) are assessed in clinical trials by a variety of physical examination instruments. At the 2010 annual meeting of the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA), members were updated on the development and availability of modules that teach these instruments. Web-based interactive multimedia presen...

Psoriasis is a worldwide chronic inflammatory disease, involving both skin and joints. In order to characterize psoriasis in Han Chinese population, we conducted this nationwide prospective and hospital based survey, in which 56 hospitals with departments of dermatology participated, located in 33 cities across China. A total of 12,031 outpatients with psoriasis were registered during 2009 to 2...

OBJECTIVE To determine the frequency of anxiety and depression in patients with psoriasis. STUDY DESIGN Cross-sectional study. PLACE AND DURATION OF STUDY Outpatient Departments of Dermatology and Psychiatry, Ziauddin University Hospital, KDLB Campus, Karachi, from October 2005 to September 2006. PATIENTS AND METHODS All patients presenting with psoriasis vulgaris above the age of 15 year...