Identifying the molecular mechanisms underlying OL development is not only critical to furthering our knowledge of OL biology, but also has implications for understanding the pathogenesis of demyelinating diseases such as Multiple Sclerosis (MS). Cellular development is commonly studied with primary cell culture models. Primary cell culture facilitates the evaluation of a given cell type by pro...

Organizational learning (OL) is a major weakness for ERP project implementation. Exploratory research interviews of ERP managers/consultants support this finding. Many organizations do not implement proper procedures that effectuate valid learning experiences from failures endured. The literature suggests that effective OL involves complex ongoing processes requiring pervasive knowledge managem...

In this study, the structural changes of alkali lignin induced by ozonation were investigated, and effect ozone-treated its mechanism on Avicel enzymatic hydrolysis was examined. The physicochemical properties analyzed FTIR, 1H-13C HSQC NMR, GPC. It revealed that ozone pretreatment increased content carboxyl and/or aldehyde groups negative zeta potential lignin, which enhanced electrostatic rep...

INTRODUCTION Point-of-care ultrasound (POCUS) is a novel technique for the assessment of jugular venous pressure. Distance education may allow for efficient dissemination of this technique. We compared online learning to a live course for teaching ultrasonography jugular venous pressure (u-JVP) to determine if these teaching methods yielded different levels of comfort with and use of u-JVP. M...

In the past decades, there has been great progress in development of organic and inorganic optical limiters with large nonlinear optical (NLO) response. Carbon-based materials, including carbon black suspension (CBS), singleand multi-walled carbon nanotubes (CNTs), 3] and some small p-electron systems, such as fullerenes, porphyrins, and phthalocyanines have been widely explored as advanced opt...

BACKGROUND Renal renin-angiotensin system (RAS) activation is one of the important pathogenic mechanisms in the development of diabetic nephropathy in type 2 diabetes. The aim of this study was to investigate the effects of a sodium-glucose co-transporter 2 (SGLT-2) inhibitor, dapagliflozin, on renal RAS in an animal model with type 2 diabetes. METHODS Dapagliflozin (1.0 mg/kg, OL-DA) or vogl...

Abstract By monitoring biomarkers in urine, personal exposure to selected chemical substances can be assessed. In this paper, we describe the of 7 benzophenone and 2 camphor UV-filters 11 metabolites polycyclic aromatic hydrocarbons (OH-PAHs) 454 urine samples collected from mothers new-borns an industrial (Karvina) reference area (Ceske Budejovice) over winter summer seasons. The analytical me...

A constructive method for investigating if a given nonlin-ear dynamic system subject to control constraints can be controlled to follow a desired curve in the state or output space is presented. If the method gives an aarmative answer we can compute a closed form expression of the corresponding state feedback control law. Specifying a family of parametrized curves, approximations of reachable s...

Presilphiperfolanols (also known as prebotrydials) are members of a family of natural products that are important biosynthetic precursors to diverse sesquiterpenoids (Figure 1).[i, ii, iii, iv] To date, four members of the group have been isolated: presilphiperfolan-1-ol (1),[v] 9-epi-presilphiperfolan-1-o l (2),[vi] presilphiperfolan-8-ol (3),[ii] and presilphiperfolan-9-ol (4),[vii] with 1 an...