Component signaling in taste mixtures containing both beneficial and dangerous chemicals depends on peripheral processing. Unidirectional mixture suppression of chorda tympani (CT) nerve responses to sucrose by quinine and acid is documented for golden hamsters (Mesocricetus auratus). To investigate mixtures of NaCl and acids, we recorded multifiber responses to 50 mM NaCl, 1 and 3 mM citric ac...

Effects of gustatory nerve transection on salt taste have been studied extensively in rats and hamsters but have not been well explored in the mouse. We examined the effects of chorda tympani (CT) nerve transection on NaCl taste preferences and thresholds in outbred CD-1 mice using a high-throughput phenotyping method developed in our laboratory. To measure taste thresholds, mice were condition...

Atchison DK, Westrick E, Szandzik DL, Gordish KL, Beierwaltes WH. Parathyroid hormone-related protein stimulates plasma renin activity via its anorexic effects on sodium chloride intake. Am J Physiol Endocrinol Metab 303: E457–E463, 2012. First published May 29, 2012; doi:10.1152/ajpendo.00020.2012.—Parathyroid hormone-related protein (PTHrP) increases renin release from isolated perfused kidne...

High-pressure powder x-ray diffraction experiments using synchrotron radiation are performed on the yttrium monochalcogenides YS, YSe, and YTe up to a maximum pressure of 23 GPa. The ambient NaCl structure is stable throughout the pressure range covered. The bulk moduli are determined to be 93, 82, and 67 GPa for YS, YSe, and YTe, respectively. First-principles total energy calculations are car...

Cellulose acetate (CA) and Tween-20(T-20) are interacted and resulted as a supported liquid membrane system. The membrane potential was measured with uni-uni valent electrolyte, NaCl solutions using saturated calomel electrodes (SCEs).The effective fixed charge density of the membrane was determined by TMS method. Other important electrochemical parameters were calculated. Membrane adsorb-abili...