DNA N(6)-methyladenine (6mA) modification is commonly found in microbial genomes and plays important functions in regulating numerous biological processes in bacteria. However, whether 6mA occurs and what its potential roles are in higher-eukaryote cells remain unknown. Here, we show that 6mA is present in Drosophila genome and that the 6mA modification is dynamic and is regulated by the Drosop...

Introduction: Colonoscopy is an invasive method that is painful for patient especially for children. The objective of this research was investigation into the effect of supermint oral drop (peppermint essence) on the patient and colonoscopist group satisfaction during colonoscopy.   Material and Methods: In this clinical trial study, 101 children candidate colonoscopy (7-14 years old) in childr...

The N, S-co-doping of commercial carbon nanotubes (CNTs) was performed by a solvent-free mechanothermal approach using thiourea. CNTs were mixed with the S-dual precursor in ball-milling apparatus, and further thermally treated under inert atmosphere between 600 1000 °C. influence temperature applied during thermal procedure investigated. Textural properties materials not significantly affected...

The peroxisome proliferator-activated receptors (PPARs) are a family of nuclear transcription factors thought to act as receptors for polyunsaturated fatty acids and to reduce production of series 2 prostaglandins (PG). The objective of this study was to investigate the effect of different ratio n-6:n-3 on the PPAR expression of rats endometrial tissue. The findings obtained from this study sho...

Recombinant FVIII manufacturing is characterized by poor product stability and low yields. Codon-optimization of transgenes accelerates translation by exploiting the synonymous codon usage bias of a species. However, this can alter the performance of the final product. Additionally, the effects of transgene design across diverse cell types are not well understood and are of interest for next-ge...

Resistance to neuraminidase inhibitors (NAIs) is a growing problem in battle against influenza A virus. However, little is known about the resistance of viruses isolated from dabbling ducks, the natural reservoir of the influenza virus. To our knowledge, no low-pathogenic avian influenza (LPAI) virus resistant to NAIs has been detected. The aim of this study was to investigate mallard isolates ...

Kuznar’s (CA 42:432–40) proposed relationship between social status (wealth), risk preference, and utility bears further scrutiny. The author proposes “that there will be a general curvilinear relationship between wealth and risk sensitivity in which the poor and the wealthy will prefer risky prospects whereas those with more moderate wealth will be risk-averse” (p. 437). He attempts to clarify...