Sexually transmitted diseases (STDs), including urethritis caused by gonococcus and Chlamydia trachomatis, are of increasing public health importance (1, 3, 6, 7, 9). The common occurrence of coinfections and the emergence of antimicrobial resistance of both pathogens emphasize the need for a single broadly active drug for management of these STDs (2, 3, 7, 9, 11–13). Penicillins and other beta...