[email protected] Introduction Leiomyosarcoma is a rare sarcoma that usually originates in the retroperitoneum, thus often occurring in the uterus. It more rarely originates intramuscularly in the peripheral somatic soft tissue. Myxoid leiomyosarcoma, in which the myxoid stroma occupies more than 50% of the tissues, is also rarely reported as the myxoid variant of leiomyosarcoma. The pre...

BACKGROUND Extraskeletal myxoid chondrosarcoma is a rare soft tissue sarcoma that has unusual ultrastructural and molecular features. However, unlike other soft tissue sarcomas, it does not have specific clinical symptoms or radiological features, which can make its diagnosis difficult. Nevertheless, extraskeletal myxoid chondrosarcoma has a rare gene fusion (EWSR1-NR4A3) that is useful for mak...

Aggressive Angiomyxoma (AA) is a rare, locally aggressive mesenchymal neoplasm that commonly involves the vulvoperineal region of females in reproductive age [1]. Steeper and Rosai first mentioned the term “aggressive angiomyxoma” in 1983 and considered it to be a rare benign mesenchymal tumor with a locally aggressive nature [9-11]. Aggressive angiomyxoma commonly presents as a painless, gelat...

Nerve sheath myxoma (neurothekeoma) are rare benign nerve sheath tumors, usually arising in the skin of the head and neck region and upper extremities in young females. To the best of author's knowledge only two cases of intracranial neurothekeoma have been published in the English literature. These tumors were located in the parasellar area and in middle cranial fossa. This is ...

Aims. Chondroid lipoma (CL) is a benign tumor that mimics a variety of soft tissue tumors and is characterized by translocation t(11;16). Here, we analyze CL and its histological mimics. Methods. CL (n = 4) was compared to a variety of histological mimics (n = 83) for morphological aspects and immunohistochemical features including cyclinD1(CCND1). Using FISH analysis, CCND1 and FUS were invest...

Primary lung sarcomas are rare but aggressive tumors accounting for less than 0.5% of all lung tumors. The diagnosis of primary lung sarcoma should only be considered after exclusion of other sites. A 32-year-old female presented with recurrent hemorrhagic pleural effusions, shortness of breath and persistent cough. Pleural effusion was drained twice, and each time its analysis was normal. Pati...

Myoepitheliomas are benign tumors which account for less than 1% of all salivary gland tumors. In this article, we report the clinical, pathologic, and immunohistochemical features of plasmacytoid myoepithelioma of the hard palate in a 73-year-old man having a painless hard palate mass with progressive growth for one month who was admitted in Alzahra Hospital of Isfahan University of Medical Sc...

neoplastic soft tissue masses. Although it contains a relatively small amount of somatic soft tissue elements, the foot is rich in tendons, fasciae, retinaculae, and synovium (1). In the Armed Forces Institute of Pathology series[LKH1], 8% of benign soft-tissue tumors and 5% of malignant soft-tissue tumors occurred in the foot and ankle, suggesting an unexpectedly high incidence on a tissue vol...