BACKGROUND The safety and predictability of refractive surgery for all degrees of myopia is now becoming established. It is therefore appropriate to evaluate whether there is a patient driven demand for such treatments and, if so, to establish guidelines for its provision within the National Health Service (NHS). METHODS A comparative study was designed to assess the effect of degree of myopi...

OBJECTIVE To assess the relationship of near, midworking distance, and outdoor activities with prevalence of myopia in school-aged children. DESIGN Cross-sectional study of 2 age samples from 51 Sydney schools, selected using a random cluster design. PARTICIPANTS One thousand seven hundred sixty-five 6-year-olds (year 1) and 2367 12-year-olds (year 7) participated in the Sydney Myopia Study...

purpose: to compare the safety, efficacy, and visual results of laser in situ keratomileusis (lasik) in eyes with and without previous scleral buckling surgery in the same individuals. methods: in a prospective clinical trial, 14 eyes of 7 patients with myopic refractive error and history of scleral buckling in one eye, underwent lasik surgery in both eyes according to a standard surgical proto...

The effect of myopic defocus on myopia progression was assessed in a two-year prospective study on 94 myopes aged 9-14 years, randomly allocated to an undercorrected group or a fully corrected control group. The 47 experimental subjects were blurred by approximately +0.75 D (blurring VA to 6/12), while the controls were fully corrected. Undercorrection produced more rapid myopia progression and...

Myopia continues to be a serious public health problem due the steady increase in prevalence of disease and presence complications leading loss vision. The aim study was investigate myopia among medical students. Materials methods. A self-reported questionnaire used collect myopia-related data 1st-6th year students various faculties Kazan State Medical University. assessed using record patient ...

Purpose To identify causal gene mutations in 14 families with autosomal dominant (AD) high myopia using exome sequencing. Methods Select individuals from 14 large Caucasian families with high myopia were exome sequenced. Gene variants were filtered to identify potential pathogenic changes. Sanger sequencing was used to confirm variants in original DNA, and to test for disease cosegregation in...

PURPOSE Myopia, or near-sightedness, is one of the most common human visual impairments worldwide, and high myopia is one of the leading causes of blindness. In this study, we investigated the mutation spectrum of ZNF644, a causative gene for autosomal dominant high myopia, in a high-myopia cohort from a Chinese population. METHODS DNA was isolated with the standard proteinase K digestion and...

AIMS To assess the longitudinal changes in biometric parameters and associated factors in young myopic children aged 7--9 years followed prospectively in Singapore. METHODS Children aged 7--9 years from three Singapore schools were invited to participate in the SCORM (Singapore Cohort study Of the Risk factors for Myopia) study. Yearly eye examinations involving biometry measures were perform...

While instrument myopia is known to occur when microscopes are used, little is known about the accommodation response during microscopy, or about the factors which may alter the magnitude of instrument myopia. In addition, there has been no real-time objective measurement of instrument myopia during the microscopy task. Twenty inexperienced subjects and 10 experienced microscopists (average wor...

The available evidence suggests that both genes and environment play a crucial role in the development of juvenile onset myopia. When the human visual system is examined from an evolutionary perspective, it becomes apparent that humans, living in the original environmental niche (hunter-gatherer) for which our species is genetically adapted, are either slightly hypermetropic or emmetropic and r...