introduction: the purpose of this study was to evaluate the antimicrobial photodynamic therapy (apdt) and low level laser therapy (lllt) on wound healing, pain intensity, swelling problems, halitosis and the postoperative usage of analgesics after surgical removal of lower third molars. methods: one hundred and fifty patients, randomly divided into three groups were selected (50 per each group)...

Purpose Scleral cross-linking (SXL) with a photosensitizer and light is a potential strategy to mechanically reinforce the sclera and prevent progressive axial elongation responsible for severe myopia. Current approaches for light delivery to the sclera are cumbersome, do not provide uniform illumination, and only treat a limited area of sclera. To overcome these challenges, we developed flexib...

To study the solid state (1)H-DNP mechanism of the biradical TOTAPOL under static conditions the frequency swept DNP enhancement spectra of samples containing 20 mM and 5 mM TOTAPOL were measured as a function of MW irradiation time and temperature. We observed that under static DNP conditions the biradical TOTAPOL behaves similar to the monoradical TEMPOL, in contrast to MAS DNP where TOTAPOL ...

The utilization of green chemistry techniques is dramatically reducing chemical waste and reaction times as has recently been proven in several organic syntheses and chemical transformations. To illustrate these advantages in the synthesis of bioactive heterocycles, we have studied various environmentally benign protocols that involve greener alternatives. Microwave (MW) irradiation of neat rea...

The immunological effects of visible and infrared light from laser and non-laser sources have remained insufficiently studied, which has restricted the use of light in the treatment of diseases associated with immune system disorders. The present randomised, placebo-controlled double-blind trial was designed to study changes in the humoral immunity of a large group of volunteers after exposure ...

This study was performed to determine whether modulation of light delivery could improve tumour kill in photodynamic therapy (PDT) of brain tumours, as optimal dosimetry has not been fully established. One hundred and sixty-five adult Wistar rats were treated, of which 70 had an implanted C6 cerebral glioma. Haematoporphyrin derivative (HpD) was injected at doses between 0 and 20 mg/kg, 24 h pr...

PURPOSE We tested for protection of blue light-exposed A2E-containing retinal pigment epithelial (RPE) from damage through the implementation of polycarbonate filters containing varying levels of a pigment that absorbs short wavelength light. METHODS Human adult RPE cells (ARPE-19) that had accumulated synthesized A2E were exposed to either a light line delivered from a tungsten halogen sourc...

We report a strategy to fabricate a rapid and stable surface-enhanced Raman scattering (SERS)-based hybrid nanomaterial using gold nanopopcorns attached single-walled carbon nanotubes (AuNP@f3-SWCNTs) for label-free detection and photothermal killing of bacteria. Herein, previously ester-functionalized single-walled carbon nanotubes (f1-SWCNTs) undergo 1,3-dipolar cycloaddition reaction with in...

In this article we suggest a new concept for cell destruction based upon manipulating magnetic nanoparticles (MNPs) by applying external, low frequency alternating magnetic field (AMF) that oscillates the particles, together with focused laser illumination. Assessment of temperature profiles in a head and neck squamous cell carcinoma sample showed that cells with MNPs, treated with AMF (3 Hz, 3...

Azide terminally functional poly(methyl methacrylate)s (Mn = 4000-6000, PDI = 1.21-1.28) have been prepared by living radical polymerization and successfully reacted with alkynes in a Huisgen cycloaddition (click) reaction in one pot using the same catalyst for both processes.