Multiple Sclerosis (MS) is a disease with a wide-ranging impact on functional status. The aim of the study was to examine the added value of simultaneously evaluating fatigue, personal ADL and handwriting performance as indicators for functional decline among patients with MS. Participants were 50 outpatients with MS and 26 matched healthy controls. Data collection instruments included a disabi...

BACKGROUND What currently appears to be irreversible axonal loss in normal appearing white matter, measured by proton magnetic resonance spectroscopy is of great interest in the study of Multiple Sclerosis. Our aim is to determine the axonal damage in normal appearing white matter measured by magnetic resonance spectroscopy and to correlate this with the functional disability measured by Multip...

This work proposes two enhanced multiple mobile subscriber stations (MSSs) power-saving scheduling methods for IEEE802.16e broadband wireless networks. The proposed methods are designed for the Unsolicited Grant Service (UGS) of IEEE802.16e. To reduce the active periods of all power-saving MSSs, the base station (BS) allocates each MSS fewest possible transmission frames to retrieve its data fr...

Objective. To compare patterns of associations of changes in mental and physical health dimensions of health-related quality of life (HRQoL) over time with relapse occurrence and changes in Expanded Disability Status Scale (EDSS) scores in patients with relapsing multiple sclerosis (RMS). Methods. This 24-month, phase IV, observational study enrolled 334 patients with RMS who received interfero...

BACKGROUND Several studies reported olfactory dysfunction in patients with multiple sclerosis. The estimate of the incidence of olfactory deficits in multiple sclerosis is uncertain; this may arise from different testing methods that may be influenced by patients' response bias and clinical, demographic and cognitive features. AIMS To evaluate objectively the olfactory function using Olfactor...

introduction: multiple sclerosis is a chronic inflammatory disease of central nervous system. the etiology of ms is slightly known, but genetic and environmental factors are reported. vitamin d regulates gene expression and affects target cell functions. the aim of this study was to investigate the expression variation of il-2 and il-4 genes under vitamin d supplementation in patients with mult...

Background: Multiple Sclerosis (MS) is chronic and debilitating neurological disease which occurs between the ages of 20 and 40 years. Myelin degradation is common in certain areas such as the optic nerve, brain stem, and cerebellum, which causes problems such as imbalance, inability to perform daily tasks, and ultimately affects and reduces the self-efficacy of the affected individuals. Objec...

melatonin has both pro-inflammatory and anti-inflammatory properties depending on the stage of inflammation. despite its therapeutic effect in alleviation of some symptoms of multiple sclerosis; the precise role of melatonin in ms pathogenesis remains a topic of debate. the aim of this study was to measure the urine level of one of melatonin products which is an index of serum melatonin level, ...