Intracranial hemangiopericytoma (HPC) is a rare brain tumor with aggressive biologic behavior associated with high recurrence rate and often with extracranial metastasis. The most common sites of extracranial metastasis of the intracranial HPC are the long bones, lung, liver and abdominal cavity in the order of frequencies. Extracranial metastases usually occur long after the initial diagnosis ...

Brain tumors are common solid pediatric malignancies and the main reason for cancer-related death in setting. Recently, evidence has revealed that noncoding RNAs (ncRNAs), including microRNAs (miRNAs), long ncRNAs (lncRNAs), circular (circRNAs), play a critical role brain tumor development progression. Therefore, this review article, we describe functions molecular mechanisms of multiple types ...

primary lymphomas of the lung are rare and usual radiographic findings are adenopathy, effusion, multiple lesions, solitary lesion or diffuse lesion. this paper presents a case of primary malignant tumor of the lung with a very rare radiological presentation. a 20-year-old male patient was admitted to our hospital due to fever, chills, productive cough and later development of hemoptysis. weigh...

echinococcus granulosus is considered the major cause of human hydatid cysts. usually the duration of cyst formation is 10-20 years. this period shortens significantly upon rupture of a primary cyst. the literature describes low incidence of primary involvement of ovary as a site of hydatid cyst formation. our case is the first report on ovarian hydatid cyst in iran. a 60-year-old woman was pre...

Introduction: Glioblastoma multiforme (GBM) is the most common and aggressive primary malignant brain tumor found in adults. GBM has limited therapeutic options. Initial sampling establishes histopathologic diagnosis, identifies prognostic biomarkers, provides an opportunity for molecular profiling. By contrast, utility of repeat profiling recurrent not well established.

glioblastoma is the most common and the most lethal primary brain cancer. this malignancy is highly locally invasive, rarely metastatic and resistant to current therapies. little is known about the distinct molecular biology of glioblastoma multiforme (gbm) in terms of initiation and progression. so far, several molecular mechanisms have been suggested to implicate in gbm development. homeodoma...

Glioblastoma is the most common and aggressive primary brain cancer. Recent isolation and characterization of brain tumor-initiating cells supports the concept that transformed neural stem cells may seed glioblastoma. We previously identified a wide array of mesenchymal tissue transcripts overexpressed in a broad set of primary glioblastoma (de novo) tumors but not in secondary glioblastoma (de...

Brain metastases arise in 10%-40% of all cancer patients. Up to one third of the patients do not have previous cancer history. We report a case of a 67-years-old male patient who presented with confusion, tremor, and apraxia. A brain MRI revealed an isolated right temporal lobe lesion. A thorax-abdomen-pelvis CT scan showed no primary lesion. The patient underwent a craniotomy with gross-total ...

objective: to report involvement of the central nervous system (cns) following epithelial ovarian cancer is rare. advances in management of ovarian cancer by use of primary surgery including abdominal hysterectomy, bilateral salpingo'oophorectomy should attain as complete a cytoreduction as possible and effective platinum-based chemotherapy have prolonged survival. case report: we present a cas...

BACKGROUND Many of the current standard therapies employed for the management of primary malignant brain cancers are largely viewed as palliative, ultimately because these conventional strategies have been shown, in many instances, to decrease patient quality of life while only offering a modest increase in the length of survival. We propose that caloric restriction (CR) is an alternative metab...