Stirring Lewis-basic transition metal complexes with the salts M[BAr(Cl)4] (M = Ag, Tl; Ar(Cl) = 3,5-C6H3Cl2) resulted in the formation of diplatinum complexes [{(Cy3P)2Pt}2(μ-Ag)][BAr(Cl)4] (3) and [{(Cy3P)2Pt}2(μ-Tl)][BAr(Cl)4] (4) and the diiron compound [{(OC)3(Me3P)2Fe}2(μ-Ag)] (5) featuring bridging, unsupported metal cations. Their properties were investigated by multinuclear NMR spectro...

The assembly formation of Zn cluster compounds comprising pyridinealcohol ligands is described and their solution and solid state features have been determined using NMR spectroscopy and X-ray diffraction. The di-Zn complex 5 and tetra-Zn complex 7 may serve as accessible structural models for the active site of various multinuclear Zn-containing metalloenzymes. Their phosphoester cleavage acti...

Ssu72 helps regulate transcription and cotranscriptional mRNA processing by dephosphorylating serine residues at the 5th position in the heptad repeats of the C-terminal domain of RNA polymerase II. Here we use multidimensional, multinuclear NMR experiments to assign the backbone and side-chain resonances of the 23 kDa Ssu72 from Drosophila melanogaster in the phosphate-bound state, and use NMR...

The ‘living’ species selenide anion Se2, generated in situ by the reduction of 1,2-bis(bis(4-chlorophenyl)methyl)diselane with sodium borohydride, was treated with various organic halides to afford synthetically important organoselenium compounds including α,ω-diselenoethers and selenides bearing ester functionality, under mild and neutral conditions. These compounds have been characterized ana...

The coordination chemistry of a series of pro-ligands ([L¹]-[L⁶]) with cobalt and zinc derivatives has been studied. All complexes have been characterized by multinuclear NMR, elemental analysis, and by single-crystal X-ray diffraction studies. Polymerization of rac-lactide takes place at 130 °C in the presence of cobalt and zinc complexes to yield polymers under solvent free conditions with co...

The toluene solution structure of an N-lithio(triphenyl)phosphazene (Ph(3)PNLi) mixed aggregate with lithium bromide (LiBr), 5, has been elucidated for the first time based on multinuclear magnetic resonance measurements ((1)H, (6)Li, (7)Li, (13)C and (31)P). The structure consist of two dimers [Li(mu-Z)](2) (Z= Br, NPR(3)) linked through LiX (X= N, Br) bridges. This arrangement is a cubane-lik...

receptor positive but require RANKL for bone resorption. Michael S. Kim, Chris J. Day, Christina I. Selinger, Carly L. Magno, Sebastien J.R. Stephens and Nigel A. Morrison*. From the School of Medical Science, Griffith University Gold Coast Campus, Queensland, 4215, Australia. Running Title: MCP-1 mediated TRAP+ multinuclear cells. Address correspondence to: Nigel A. Morrison, School of Medical...

receptor positive but require RANKL for bone resorption. Michael S. Kim, Chris J. Day, Christina I. Selinger, Carly L. Magno, Sebastien J.R. Stephens and Nigel A. Morrison*. From the School of Medical Science, Griffith University Gold Coast Campus, Queensland, 4215, Australia. Running Title: MCP-1 mediated TRAP+ multinuclear cells. Address correspondence to: Nigel A. Morrison, School of Medical...

The construction of novel (macrocyclic) multinuclear Co(III)salen catalysts is reported. Olefin metathesis has been used as a key construction tool for the multimetallic structures starting from versatile allyl-substituted salen scaffolds. The Co(III) complexes were tested in the hydrolytic kinetic resolution of (rac)-1,2-epoxyhexane and epoxide ring opening reactions using methanol as the nucl...

Bacteriophage λ protein phosphatase (λPP) with Mn2+ as the activating metal cofactor was studied using phosphatase inhibition kinetics and electron paramagnetic resonance (EPR) spectroscopy. Orthophosphate and the oxoanion analogues orthovanadate, tungstate, molybdate, arsenate, and sulfate were shown to inhibit the phosphomonoesterase activity of λPP, albeit with inhibition constants (Ki) that...