Following the publication of Lillie's (1917) observations and theories on the endocrine basis of the development of the bovine freemartin, experiments were initiated to determine if heterosexual gonad grafts to the chorio-alantoic membrane of chicks could stimulate formation of intersexes (Willier, 1927). Hormone extracts of testes and urine were used by Dantchakoff (1935) and Kozelka & Gallagh...

Persistent Mullerian Duct Syndrome is a rare autosomal recessive disease characterized by persistent Mullerian derivative in patients with 46 XY Karyotype and normal virilization .Here we are presenting a case of incidental finding of Persistent Mullerian Duct Remnants in a 58 yr old man during routine hernioplasty.Histological diagnosis was confirmed by Immunohistochemistry

background: reduced ovarian reserve has been known to predict poor ovarian response and poor success rates in infertile women undergoing assisted reproductive technology. ovarian reserve also decreases with age but the rate of decline defers from a woman to another. the aim of this study was to detect any difference in ovarian reserve as measured by basal serum fsh and amh between matched cohor...

Introduction: Breast cancer is the second most common in premenopause age, has a better outcome now. Increasing early detection rates and effectiveness of adjuvant chemotherapy treatments are factors that influence prognosis dan survival rate. However, treatment can lead to ovarian dysfunction resulting decreased quality life.Case: A-29-year-old woman with breast received regimen Docetaxel, Dox...

Abstract Background Persistent Mullerian Duct Syndrome (PMDS) is a type of pseudo-hermaphroditism occurring in males internally due to failure the Anti Hormone (AMH)-dependent sex differentiation pathway. Due absent (AMH), adult male has both Wolffian and duct derivatives. Considering limited information available existing literature, malignant transformation PMDS rarely been reported. Case Pre...

Mammalian male fertility relies on complex inter- and intracellular signaling during spermatogenesis. Here we describe three alleles of the widely expressed A-kinase anchoring protein 9 (Akap9) gene, all of which cause gametogenic failure and infertility in the absence of marked somatic phenotypes. Akap9 disruption does not affect spindle nucleation or progression of prophase I of meiosis but d...

First described in 2005, the Mullerian derived cyst in the mediastinum is a rare finding with few subsequent reports. We report a case of Mullerian cyst occurring in the mediastinum of a 49-year-old female that was resected by robot-assisted thoracoscopic surgery. To our knowledge, this is the first report of robot-assisted resection of Hattori's cyst. Histopathologic analysis revealed ciliated...