In induction of systemic and mucosal immunity, particulate antigens are more effective than soluble antigens possibly because they are more efficiently endocytosed by mucosal-associated lymphoid tissue (MALT) M cells. In this study, we determined the systemic and mucosal immune responses in rabbits following intranasal immunization of tetanus toxoid TT and CpGODN encapsulated within PLGA nanosp...

We report here a patient with mucosa associated lymphoid tissue (MALT)-lymphoma of the breast complicated with Sjögren syndrome. It is speculated that Ga-67 could accumulate not only in lymphoma lesions but also in benign lymphoproliferative locations of Sjögren syndrome. Gallium-67 scintigraphy might be useful for the diagnosis and therapeutic monitoring of MALT-lymphoma complicated with Sjögr...

Primary malignant lymphoma of the trachea is rare. The case history is presented of a 44 year old woman with a mucosa-associated lymphoid tissue (MALT) lymphoma of the trachea who was treated with a tracheal resection and reconstruction. The patient has been free from the disease for 53 months, which confirms the favourable prognosis of MALT lymphoma following local treatment.

Synchronous malignant mucosa associated lymphoid tissue MALT-lymphoma of the small bowel and adenocarcinoma of the colon in the same patient is a scarce rarity. Only few cases have been reported so far. Thus, it might be of interest to report such a case of coexisting malignant MALT-lymphoma of the duodenum and adenocarcinoma of the large bowel.

BACKGROUND The gastric lesions of various lymphomas were observed at the cellular level using endocytoscopy. METHODS Endocytoscopy and magnifying endoscopy with narrow band imaging (NBI) were performed in 17 patients with lymphomas of the stomach. The lesions consisted of 7 with low-grade mucosa-associated lymphoid tissue (MALT), 5 with gastric involvement by adult T-cell leukemia/lymphoma (A...

In approximately 5% to 10% of gastric mucosa-associated lymphoid tissue (MALT) lymphomas, evidence of Helicobacter pylori infection is absent, and their pathogenesis is poorly understood. We reviewed the clinical data and histology, and we examined t(11;18)(q21;q21) and BCL10 expression pattern in 17 such cases. In each case, the absence of H pylori was confirmed by negative serology and histol...

A 36-year-old Japanese woman presented with extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) in the stomach. The gastric lesions only partially improved after eradication therapy for Helicobacter pylori. A fluorescence in situ hybridization analysis revealed no fusion genes of API2-MALT1, although trisomy of chromosome 18 was identified. Radiation therapy w...

Primary hepatic extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT) type lymphoma is very rare disease. We reported two cases of primary hepatic MALT lymphoma associated with chronic inflammatory disorder. One case was a 74-year-old female complicated with asymptomatic primary biliary cirrhosis. Another case was a 73-year-old man presented with a mild hepatitis C. Both...

We present a case of a 56-year-old man with 3 synchronous gastric tumors. The patient presented with melena, and 3 gastric abnormalities were detected on gastroduodenoscopic examination, including a small ulcerative lesion in the gastric antrum, a submucosal mass in the gastric body, and severe erosion in the fundus. Histological examination of biopsy samples yielded respective diagnoses of gas...

Infections have been proposed as initiating factors for inflammatory disorders; however, identifying associations between defined infectious agents and the initiation of chronic disease has remained elusive. Here, we report that a single acute infection can have dramatic and long-term consequences for tissue-specific immunity. Following clearance of Yersinia pseudotuberculosis, sustained inflam...