نتایج جستجو برای: muco ciliary clearance

تعداد نتایج: 56741  

Journal: :Circulation 2012
Nader Nakhleh Richard Francis Rachel A Giese Xin Tian You Li Maimoona A Zariwala Hisato Yagi Omar Khalifa Safina Kureshi Bishwanath Chatterjee Steven L Sabol Matthew Swisher Patricia S Connelly Mathew P Daniels Ashok Srinivasan Karen Kuehl Nadav Kravitz Kimberlie Burns Iman Sami Heymut Omran Michael Barmada Kenneth Olivier Kunal K Chawla Margaret Leigh Richard Jonas Michael Knowles Linda Leatherbury Cecilia W Lo

BACKGROUND Patients with congenital heart disease (CHD) and heterotaxy show high postsurgical morbidity/mortality, with some developing respiratory complications. Although this finding is often attributed to the CHD, airway clearance and left-right patterning both require motile cilia function. Thus, airway ciliary dysfunction (CD) similar to that of primary ciliary dyskinesia (PCD) may contrib...

Journal: :archives of clinical infectious diseases 0
abbas fadaii department of internal medicine, faculty of medicine, shahid beheshti university of medical sciences, tehran, ir iran; department of internal medicine, faculty of medicine, shahid beheshti university of medical sciences, tehran, ir iran. tel.: +98-2122580333, fax: +98-2122580335 bahador bagheri department of pharmacology, faculty of medicine, semnan university of medical sciences, semnan, ir iran

tracheomegaly or tracheobronchomegaly is a rare syndrome which is characterized by dramatic dilatation of the trachea and the major bronchi. this syndorme is usually associated with chronic respiratory infection and airway obstruction. in this paper, a case with tracheomegaly and bronchiectasis was scrutinized.

Journal: :Pharmaceutics 2021

The aim of this study was to develop an intranasal in situ thermo-gelling meloxicam-human serum albumin (MEL-HSA) nanoparticulate formulation applying poloxamer 407 (P407), which can be administered liquid state into the nostril, and increase resistance against mucociliary clearance by sol-gel transition on nasal mucosa, as well improve drug absorption. Nanoparticle characterization showed that...

2015
M. Chitra S. Radhakrishnan

A Cylindrical two layer fluid model for the transport of serous and mucus layer in the human trachea and the steady state condition due to cilia beating, some immotile cilia forming porous bed in serous sub -layer in contact with the epithelium and air motion by considering mucus as a visco-elastic fluid are studied. The effect of air-motion due to forced expiration and other processes is consi...

2015
Mathias Munkholm Kim Gjerum Nielsen Jann Mortensen

BACKGROUND We aimed to evaluate and define the general clinical applicability and impact of pulmonary radioaerosol mucociliary clearance (PRMC) on the work up of patients suspected of having primary ciliary dyskinesia (PCD). In addition, we wanted to evaluate the accuracy of the reference values used in the PRMC test. METHODS Measurement of PRMC after inhalation of (99m)Tc-albumin colloid aer...

Journal: :Journal of applied physiology 2010
Timothy E Corcoran

MUCOCILIARY CLEARANCE plays a crucial host-defense role in both the upper and lower airways, providing protection from a wide variety of airborne hazards including allergens, pathogens, and environmental toxins. Proper function of the mucociliary clearance system depends on the structure and function of the cilia as well as the composition of the airway surface liquid layer. The mucus component...

Journal: :SN applied sciences 2021

Abstract In this study heat transfer effects on cilia induced mucus flow in human airways is presented. The elliptic wave pattern of tips produces metachronal which enables the transportation highly viscous with nonzero inertial forces. Upper Convective Maxwell model considered as mucus. governing partial differential equations are transformed from fixed frame to by using Galilean transformatio...

2003
RONALD E. GORDON KEITH B. WILLIAMS SAUL PUSZKIN

Metachronal beating of cilia of epithelial surfaces of most respiratory airways moves the overlying mucous layer in a caudal direction. The molecular mechanisms controlling ciliary beat remain largely unknown. Calcium, an element in its cationic form, is ubiquitous in biological functions and its concentration is critical for ciliary beating. Calmodulin, a calciumbinding protein which regulates...

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