Materials and Methods: The subjects were 36 systemically healthy, non-smoking patients (34-66 years old). All patients presented moderate-to-advanced chronic periodontitis and had at least 5 teeth and 2 pocket sites with probing depth ≥ 5 mm in each quadrant and bone loss. Then, they were randomly distributed to 3 different groups. 1. conventional quadrant-wise mechanical debridement (QMD): sup...

Introduction: To evaluate the effects of using sodium hypochlorite irrigant on pull-out bond strength of self-etch and self-adhesive resin cements to dentin. Methods: Sixty intact premolars were decoronated and the root canals were prepared by step-back technique. The teeth were divided into two groups according to the irrigant used during root canal treatment: 5.25% sodium hypochlorite and nor...

The aim of the present study was to evaluate the capacity of some root canal irrigants to induce genetic damage and/or cellular death in vitro. Murine fibroblast cells were exposed to ethylenediaminetetraacetic acid (EDTA), sodium hypochlorite (NaOCl), MTAD™ and citric acid in increasing concentrations for 3 h at 37ºC. The negative control group was treated with vehicle control (phosphate buffe...

BACKGROUND Proton pump inhibitors are used in endodontic disinfection of root canals for elimination of enterococcus faecalis. This invivo study on Wistner Rats is carried out to determine antimicrobial efficacy of proton pump inhibitor in combination with sodium hypochlorite & Mixture of Isomer of tetracycline, acid and detergent (MTAD) against E. Faecalis Materials & Methods: Periapical lesio...

BACKGROUND Cytotoxicity of root canal irrigants is important due to their close contact with host tissues. The aim of this study was to assess the cytotoxic effect of NaOCl 3%, Chx 2%, and MTAD on rat periodontal ligament fibroblasts, at 0.1 and 100 µl/mL, using WST-1 colorimetric method. MATERIAL AND METHODS Rat ligamental fibroblasts were exposed to the irrigants and their viability was ass...

INTRODUCTION Bacteria are the primary etiology of pulpal and periradicular pathosis. In endodontically treated teeth with persistent infections only one or a few bacterial species are present of which the most important is Enterococcus faecalis. The aim of this study was to compare antibacterial efficacy of canal disinfectants including 5.25% sodium hypochlorite, 2% chlorhexidine, MTAD (a mixtu...

OBJECTIVES To evaluate the combined effect of a mixture of tetracycline, acid, and detergent (MTAD) and Nisin against Enterococcus faecalis (E. faecalis) and Actinomyces viscosus (A. viscosus) biofilms. METHODS This study was conducted between June and December 2013 in collaboration with Dental Caries Research Chair, College of Dentistry, King Saud University, Riyadh, Saudi Arabia. Single-spe...

3. Tasdemir T, et al. (2008). Effect of Passive Ultrasonic Irrigation on Apical Extrusion of Irrigating Solution. Eur J Dent. Methods: Measured amount of NaOCl through the apical foramen when NaOCl was left in the canal versus passive ultrasonic activation of the irrigant conclusions: PUI extruded significantly less irrigant than the control group (2.15 ± 2.73 versus 14 ± 13.03 uL, respectively...

3. Tasdemir T, et al. (2008). Effect of Passive Ultrasonic Irrigation on Apical Extrusion of Irrigating Solution. Eur J Dent. Methods: Measured amount of NaOCl through the apical foramen when NaOCl was left in the canal versus passive ultrasonic activation of the irrigant conclusions: PUI extruded significantly less irrigant than the control group (2.15 ± 2.73 versus 14 ± 13.03 uL, respectively...