Target Audience: Clinicians and researchers working with dynamic Contrast Enhanced MRA (CE-MRA). Purpose: Dynamic Magnetic Resonance Angiography (MRA) has become a widely accepted tool for clinical evaluation of complex vascular hemodynamics. To allow for high spatial and temporal resolution, view-sharing techniques 1,2 are commonly used whereby the k-space center is updated more frequently tha...

Background 3D T1-weighted contrast-enhanced MRA (CE-MRA) is routinely used for non-invasive evaluation of the thoracic aorta. However, competing demands of high spatial resolution and fast (breath-hold) acquisition often preclude ECG-gating, leading to motion artifact at the aortic root. Standard Cartesian-sampled ECG-gated CE-MRA acquires 1 partition per heartbeat resulting in long scan times,...

The purpose of this study was to determine the feasibility of using an ultrasound contrast agent test bolus to determine optimum bolus timing for three-dimensional (3D) gadolinium (Gd)-enhanced magnetic resonance angiography (MRA). Small test doses of ultrasound contrast agent (0.3 ml Optison) were injected intravenously followed immediately by a 20 ml saline flush. Arrival of the contrast agen...

Introduction Ghost imaging is a newly proposed methodology for magnetic resonance angiography (MRA) that eliminates the need for image subtraction. Using a 3D pulse sequence that acquires slices outside of the body, the method works by modulating arterial signal to produce ghost artifacts. Arterial ghost artifacts localizing in air outside of the body are then processed and viewed along multipl...

BACKGROUND AND PURPOSE A substantial percentage of coiled aneurysms are associated with persistent filling of an aneurysmal component due to incomplete initial treatment or re-growth. Traditionally follow-up of coiled aneurysms has consisted of repeated intra-arterial cerebral catheter angiography, an invasive procedure with associated risks. Hence, many authors have advocated the use of non-in...

BACKGROUND AND PURPOSE 3D time-of-flight MR angiography (3D TOF MRA) may be used as noninvasive alternative to digital subtraction angiography (DSA) for the follow-up of patients with intracranial aneurysms treated with Guglielmi detachable coils (GDCs). We aimed to determine the influence of aneurysm size and location on diagnostic accuracy of 3D TOF MRA for follow-up of intracranial aneurysms...

OBJECTIVES This national multicenter study determined the diagnostic performance of 1.5-T whole-heart coronary magnetic resonance angiography (MRA) in patients with suspected coronary artery disease (CAD). BACKGROUND Whole-heart coronary MRA using steady-state free precession allows noninvasive detection of CAD without the administration of contrast medium. However, the accuracy of this appro...

In the accompanying article, we showed that AP5A displayed heterogenous vasoactive effects in rat resistance arteries. It induced a stable vasoconstriction in the superior epigastric artery (SEA) and a transient vasoconstriction in the mesenteric resistance artery (MrA). In the phenylephrine-precontracted MrA AP5A induced a marked vasorelaxation. In this study the noncompetitive inhibition of t...