BACKGROUND c-Kit is a proto-oncogene that encodes tyrosine kinase receptor (CD117). Mean platelet volume (MPV) is a useful marker, providing information on platelet function and diameter. OBJECTIVE To investigate c-Kit expression and intensity in patients with Kaposi's sarcoma (KS) and to investigate the relation between Ki-67 proliferation and MPV. METHODS A total of 32 patients, diagnosed...

PURPOSE To evaluate the association between varicocele and MPV values in pediatric and adult patients. And its association with different clinical parameters. MATERIALS AND METHODS We retrospectively analyzed the medical charts of patients treated for varicocele at our Institution between December 2010 and December 2014. The study patients were divided into three groups: group 1- patients wit...

INTRODUCTION Platelets play a major role in thromboembolic events. Increased mean platelet volume (MPV) indicates higher platelet reactivity and also a tendency to thrombosis. Patent foramen ovale (PFO), persistence of the fetal anatomic shunt between right and left atria, is strongly associated with cryptogenic stroke. The aim of this study is to determine the relationship between MPV and PFO ...

BACKGROUND Myocardial infarction is the major cause of morbidity and mortality in industrialized countries. Platelet count and the mean platelet volume (MPV), a simple and reliable indicator of platelet size which correlates with platelet activation, might associate with troponin in acute chest pain. METHODS We analyzed MPV of 851 patients who were admitted to Rasoul-e-Akram Hospital with acu...

BACKGROUND Mean platelet volume (MPV), which is commonly used as a measure of platelet size, indicates the rate of platelet production and platelet activation. We aimed to evaluate the mean platelet volume in children with hepatitis A. METHODS In this retrospective case-controlled study, the study population consisted of 62 children with hepatitis A and 62 healthy control subjects. RESULTS ...

AIM Ventriculoperitoneal shunt infection (VPSI) is one of the main causes of mortality and morbidity in hydrocephalus. Platelet indices, mean platelet volume (MPV) and platelet distribution width (PDW) have been evaluated for some infectious diseases. In this study we aimed to investigate whether MPV and PDW values are decisive for the diagnosis of VPSI in children. MATERIAL AND METHODS Chart...

We read with great interest the article ‘Mean Platelet Volume is a useful indicator of systemic inflammation in cirrhotic patients with ascitic fluid infection’ by Suvak, et al.1 The authors concluded that MPV is increased in cirrhotic patients with ascitic fluid infection (AFI) and MPV may be a predictive test in predicting AFI. We would like to thank the authors for their valuable contributio...

AIM To investigate serum mean platelet volume (MPV) levels in acute pancreatitis (AP) patients and assess whether MPV effectively predicts the disease severity of AP. METHODS We included 117 consecutive patients with AP as the AP group and 34 consecutive patients with colorectal polyps (before endoscopic treatment) as the control group. Complete blood counts, liver function, platelet indices ...

OBJECTIVES Vasovagal syncope (VVS) is supposed to be modulated by increased sympathetic tone following an orthostatic maneuver. Increased sympathetic activity may have an important role in mean platelet volume (MPV), either by peripheral activation or by effects on thrombocytopoiesis. We aimed to show the effects of increased sympathetic activity on platelet size in patients with VVS in the pre...

BACKGROUND Subjects with high fibroblast growth factor 21(FGF21) and 23 (FGF23), endocrine hormones that regulate insulin sensitivity and phosphate metabolism, respectively, are reported to have a higher risk for adverse cardiovascular outcome. Therefore, the relationship of FGF21, FGF23, and α-Klotho (co-receptor for FGF23 signaling) with mean platelet volume (MPV) and platelet distribution wi...