نتایج جستجو برای: mpr
تعداد نتایج: 1411 فیلتر نتایج به سال:
Enzyme replacement therapy (ERT) is available for several lysosomal storage diseases. Except for Gaucher disease, for which an enzyme with exposed mannosyl residues targets mannose receptors (MR) on macrophages, ERT targets primarily the mannose 6-phosphate receptor (MPR). Most recombinant lysosomal enzymes contain oligosaccharides with both terminal mannosyl and mannose 6-phosphate residues. E...
BACKGROUND Adherence to disease-modifying therapies (DMTs) results in the reduction of the number and severity of relapses and delays the progression of multiple sclerosis (MS). Patients with lower adherence rates experience more inpatient visits and higher MS-related medical costs. Fingolimod, the first oral DMT approved by the US Food and Drug Administration, may improve the access and compli...
Through this study, the ability of a modified Peng-Robinson (MPR) equation of state in predicting the surface tension of n-alkanes based on the density functional theory approach was investigated and compared with other studies. The interfacial layer thickness and the density profile were calculated simultaneously at different temperatures from triple point to near critical point using the modi...
Article history: Received 23 April 2010 Received in revised form 22 August 2010 Accepted 23 August 2010 The present study aimed to determine the effects of maternal protein restriction on lipid metabolism of piglets at weaning and the associated underlying mechanism employing Meishan pigs as model. Sixteen Meishan sows were assigned to the control group and the maternal protein restriction grou...
The cation-dependent mannose 6-phosphate receptor (CD-MPR) is one of the two transmembrane proteins involved in transport of lysosomal enzymes. We have cloned the mouse CD-MPR gene and also a very unusual processed-type CD-MPR pseudogene. They are both present at one copy per haploid genome and map to chromosomes 6 and 3, respectively. Comparison of the complete 10-kilobase (kb) sequence of the...
Abstrak Dalam perjalanan ketatanegaraan Indonesia lembaga Majelis Permusyawaratan Rakyat (MPR) mengalami transformasi dari tertinggi negara kepada tinggi negara. Transformasi tersebut berimplikasi terhadap kewenangan MPR, dimana sebelum Amandemen Undang-Undang Dasar 1945 (UUD 1945) MPR berwenang mengeluarkan TAP MPR/S sedangkan pasca UUD menjadi tidak berwenang. Setelah diberlakukannya Undang-u...
PURPOSE The purpose of this study was to evaluate the usefulness of thick slab minimum intensity projection (MinIP) as a follow-up method in patients with pulmonary emphysema. This method was used to determine the presence or absence of changes over time in the lung field based on multi-detector-row CT (MDCT) data. METHODS Among patients diagnosed with pulmonary emphysema who underwent 16-MDC...
CTB-MPR is a fusion protein between the B subunit of cholera toxin (CTB) and the membrane-proximal region of gp41 (MPR), the transmembrane envelope protein of Human immunodeficiency virus 1 (HIV-1), and has previously been shown to induce the production of anti-HIV-1 antibodies with antiviral functions. To further improve the design of this candidate vaccine, X-ray crystallography experiments w...
Development of resistance in target pests is a major threat to long-term use of transgenic crops expressing Bacillus thuringiensis (Bt) Cry toxins. To manage and/or delay the evolution of resistance in target insects through the implementation of effective strategies, it is essential to understand the basis of resistance. One of the most important mechanisms of insect resistance to Bt crops is ...
The capacity of wireless networks can be improved by the use of multi-channel multi-interface (MCMI), multi-packet reception (MPR), and directional antenna (DA). MCMI can provide the concurrent transmission in different channels for each node with multiple interfaces; MPR offers an increased number of concurrent transmissions on the same channel; DA can be more effective than omni-DA by reducin...
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