The design of new optogenetic tools for controlling protein function would be facilitated by the development of protein scaffolds that undergo large, well-defined structural changes upon exposure to light. Domain swapping, a process in which a structural element of a monomeric protein is replaced by the same element of another copy of the same protein, leads to a well-defined change in protein ...

Résumé. Nous proposons une méthode originale pour extraire un résumé compact, représentatif et intelligible des motifs fréquents dans des données transactionnelles ou séquentielles. Notre approche consiste à extraire un nouveau type de motifs que nous appelons motifs récursifs, i.e. des motifs de motifs, à l’aide d’un algorithme hiérarchique agglomératif nommé RepaMiner. Nous générons non pas u...

ABSTRACT The objective of this research was to create museum texts and educational materials for a textiles section major year-long university exhibit focused on exploring Japanese culture aesthetics through works fine applied art. Little background information about the available. A sample historical kimono, yukata, obi in collection examined using material semiotics methods. motifs present we...

Batik is a traditional art developed in Java. has variety of motifs and it exquisite. One the valuable sources on batik classical batik, which several places Java before Indonesian independence. Besides being picturesque, also values guided by teachings Javanese culture are contained its motifs. Then used this study as basis for development manufacture contemporary decorative designs. In study,...

Almost all eukaryotic mRNAs have a poly (A) tail at the 3'-end. Canonical PAPs (PAPα/γ) polyadenylate nuclear pre-mRNAs. The recent identification of the non-canonical Star-PAP revealed specificity of nuclear PAPs for pre-mRNAs, yet the mechanism how Star-PAP selects mRNA targets is still elusive. Moreover, how Star-PAP target mRNAs having canonical AAUAAA signal are not regulated by PAPα is un...

Intracellular proteins comprise numerous peptide motifs that interact with protein-binding domains. However, using sequence information alone, the identification of functionally relevant interaction motifs remains a challenge. Here, we present a microarray-based approach for the evaluation of peptides as protein-binding motifs. To this end, peptides corresponding to protein interaction motifs w...

We report the first integrated proteomic and transcriptomic investigation of a crustacean venom. Remipede crustaceans are the venomous sister group of hexapods, and the venom glands of the remipede Xibalbanus tulumensis express a considerably more complex cocktail of proteins and peptides than previously thought. We identified 32 venom protein families, including 13 novel peptide families that ...

The essential, conserved yeast nucleolar protein Ytm1 is one of 17 proteins in ribosome assembly intermediates that contain WD40 protein-protein interaction motifs. Such proteins may play key roles in organizing other molecules necessary for ribosome biogenesis. Ytm1 is present in four consecutive 66S preribosomes containing 27SA2, 27SA3, 27SB, and 25.5S plus 7S pre-rRNAs plus ribosome assembly...

Hepatic microsomes from 5 strains of untreated mice were tested for the ability to en~ymatically cleave the nitro group from 2nitropropane (2NP). All strains showed significant NADPH-dependent nitrite release at pH 7.6 and pH 8.8. Statistical differences in nitrite-releasing activity between strains were found between BALB and PL/J and ATH strains at pH 7.6. At pH 8.8, BI0.M differed from CD-l ...

Traditional plant breeding relies on meiotic recombination for mixing of parental alleles to create novel allele combinations. Detailed analysis of recombination patterns in model organisms shows that recombination is tightly regulated within the genome, but frequencies vary extensively along chromosomes. Despite being a model organism for fruit developmental studies, high-resolution recombinat...